Bethyl Laboratories

CTHRC1 Polyclonal Antibody

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CTHRC1 Antibody (A305-863A-T) in WB

Detection of human and mouse CTHRC1 by western blot. Samples: Whole cell lysate (50 µg) from UACC-62, Malme-3M, SR, and NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified Rabbit anti-CTHRC1 antibody A305-863A-M (lot A305-863A-M-1) used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 10 seconds.

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产品信息

A305-863A-T

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

between 193 and 243

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

TBS, pH 7.0 to 8.0

内含物

0.09% sodium azide

保存条件

4° C

运输条件

Wet ice

靶标信息

The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration. CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.

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