Leinco Technologies

CTLA-4 Monoclonal Antibody (9H10), Functional Grade, In Vivo PLATINUM™

Name: CTLA-4 Monoclonal Antibody (9H10), Functional Grade, In Vivo PLATINUM\u2122
Brand: Leinco Technologies
SKU: C2841-1MG

查看其他87个CTLA-4 (CD152)抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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CTLA-4 Antibody (C2841-1MG) in WB

Western Blot analysis of CTLA-4 (CD152) in A-20 whole cell lysate and reduced recombinant mouse CTLA-4 protein using CTLA-4 Monoclonal Antibody (Product # C2841-1MG).

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产品信息

C2841-1MG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

抑制试剂 (Inhibition)

Assay-dependent

产品规格

种属反应

Mouse

宿主/亚型

Syrian hamster / IgG

分类

Monoclonal

类型

Antibody

克隆号

9H10

抗原

Mouse CTLA-4-human IgG1 fusion protein

偶联物

Functional Grade Functional Grade Functional Grade

形式

Liquid

浓度

≥5.0 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.2-7.4

内含物

no preservative

保存条件

4°C short term, -80°C long term

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Specificity: Anti-Mouse CLTA-4 (Clone 9H10) recognizes an epitope on Mouse CD152. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. This antibody was also pathogen tested and third-party certified by IDEXX BioReseach to meet the lowest mycoplasma specification and free of any viral pathogens of concern.

Endotoxin Level: <0.5 EU/mg as determined by the LAL method. Purity: >95% by SDS Page; ≥98% monomer by analytical SEC.

Product Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. Pathogen Testing: To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Leinco Purified Functional PLATINUM™ antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile.

Storage and Handling: Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80 C. Avoid Repeated Freeze Thaw Cycles.

This antibody has been tested in the following applications: Western Blotting, Blocking.

靶标信息

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.

仅用于科研。不用于诊断过程。未经明确授权不得转售。