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CTNNBIP1 Antibody (BS-4095R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with CTNNBIP1 Polyclonal Antibody, Unconjugated (bs-4095R) at 1:400 overnight at 4°C, DAB staining.
产品信息
BS-4095R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human CTNNBIP1, amino acids 3-70.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; catenin; catenin, beta interacting protein 1; Inhibitor of beta-catenin and Tcf-4
基因别名: 1110008O09Rik; 2310001I19Rik; AW457332; Catnbip1; CTNNBIP1; ICAT
UniProt ID: (Human) Q9NSA3, (Mouse) Q9JJN6
Entrez Gene ID: (Human) 56998, (Mouse) 67087, (Rat) 503000
negative regulation of transcription from RNA polymerase II promoter
branching involved in ureteric bud morphogenesis
regulation of vascular permeability involved in acute inflammatory response
anterior/posterior pattern specification
Wnt signaling pathway
negative regulation of Wnt signaling pathway
negative regulation of protein complex assembly
negative regulation of protein binding
negative regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of monocyte differentiation
positive regulation of osteoblast differentiation
negative regulation of smooth muscle cell proliferation
negative regulation of transcription initiation from RNA polymerase II promoter
negative regulation of mesenchymal cell proliferation
biological_process
