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CTNNBIP1 Antibody (MA5-44879) in IHC (P)
Immunohistochemistry analysis of CTNNBIP1 in paraffin-embedded human colon cancer tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with CTNNBIP1 Monoclonal antibody (Product # MA5-44879) using a dilution of 1:200 for 30... View More
产品信息
MA5-44879
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JE58-47
抗原
Synthetic peptide within human CTNNBIP1 aa 1-50/81.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2931335
靶标信息
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; catenin; catenin, beta interacting protein 1; Inhibitor of beta-catenin and Tcf-4
基因别名: CTNNBIP1; ICAT
UniProt ID: (Human) Q9NSA3
Entrez Gene ID: (Human) 56998
branching involved in ureteric bud morphogenesis
regulation of vascular permeability involved in acute inflammatory response
anterior/posterior pattern specification
Wnt signaling pathway
negative regulation of Wnt signaling pathway
negative regulation of protein binding
negative regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of monocyte differentiation
positive regulation of osteoblast differentiation
negative regulation of smooth muscle cell proliferation
negative regulation of transcription initiation from RNA polymerase II promoter
negative regulation of mesenchymal cell proliferation
