Product References
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Pharmacological research
Li X,Zhang Y,Zhao Y,Zhou Y,Han Q,Yang Y,Zhang L,Shi L,Jin X,Zhang R,Gao H,Xue G,Li D,Zhang ZR,Lu Y,Yang B,Pan Z
Mon Aug 01 00:00:00 EDT 2022
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Pharmacological research
Li X,Zhang Y,Zhao Y,Zhou Y,Han Q,Yang Y,Zhang L,Shi L,Jin X,Zhang R,Gao H,Xue G,Li D,Zhang ZR,Lu Y,Yang B,Pan Z
Mon Aug 01 00:00:00 EDT 2022
A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancer.
Signal transduction and targeted therapy
Xu T,Ma Q,Li Y,Yu Q,Pan P,Zheng Y,Li Z,Xiong X,Hou T,Yu B,Liu H,Sun Y
Mon Oct 17 00:00:00 EDT 2022
A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism.
iScience
Hussain M,Lu Y,Tariq M,Jiang H,Shu Y,Luo S,Zhu Q,Zhang J,Liu J
Fri Jul 15 00:00:00 EDT 2022
Early growth response-1 is a new substrate of the GSK3β-FBXW7 axis.
Neoplasia (New York, N.Y.)
Yin L,Zhang J,Sun Y
Thu Dec 01 00:00:00 EST 2022
SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma.
Journal of experimental & clinical cancer research : CR
Salaroglio IC,Belisario DC,Bironzo P,Ananthanarayanan P,Ricci L,Digiovanni S,Fontana S,Napoli F,Sandri A,Facolmatà C,Libener R,Comunanza V,Grosso F,Gazzano E,Leo F,Taulli R,Bussolino F,Righi L,Papotti MG,Novello S,Scagliotti GV,Riganti C,Kopecka J
Wed Feb 23 00:00:00 EST 2022
Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1.
Redox biology
Zhang J,Cui J,Zhao F,Yang L,Xu X,Shi Y,Wei B
Fri Oct 01 00:00:00 EDT 2021
The potential oncogenic and MLN4924-resistant effects of CSN5 on cervical cancer cells.
Cancer cell international
Zhang H,He P,Zhou Q,Lu Y,Lu B
Mon Jul 12 00:00:00 EDT 2021
Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts.
Frontiers in bioengineering and biotechnology
Zhang K,Yang R,Chen J,Qi E,Zhou S,Wang Y,Fu Q,Chen R,Fang X
Mon Sep 28 00:00:00 EDT 2020
Nedd8-activating enzyme inhibitor MLN4924 (Pevonedistat), inhibits miR-1303 to suppress human breast cancer cell proliferation via targeting p27Kip1.
Experimental cell research
Chen Y,Du M,Yusuying S,Liu W,Tan Y,Xie P
Wed Jul 15 00:00:00 EDT 2020
Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes.
Neoplasia (New York, N.Y.)
Yu Q,Hu Z,Shen Y,Jiang Y,Pan P,Hou T,Pan ZQ,Huang J,Sun Y
Wed Apr 01 00:00:00 EDT 2020
Inhibition of neddylation causes meiotic arrest in mouse oocyte.
Cell cycle (Georgetown, Tex.)
Yang M,Jin Y,Fan S,Liang X,Jia J,Tan Z,Huang T,Li Y,Ma T,Li M
Sat Jun 01 00:00:00 EDT 2019
The ubiquitin ligase SCFFBXW7α promotes GATA3 degradation.
Journal of cellular physiology
Song N,Cao C,Tang Y,Bi L,Jiang Y,Zhou Y,Song X,Liu L,Ge W
Thu Mar 01 00:00:00 EST 2018
The ubiquitin ligase SCFFBXW7α promotes GATA3 degradation.
Journal of cellular physiology
Song N,Cao C,Tang Y,Bi L,Jiang Y,Zhou Y,Song X,Liu L,Ge W
Thu Mar 01 00:00:00 EST 2018
Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.
Journal of cell science
Nagai T,Mukoyama S,Kagiwada H,Goshima N,Mizuno K
Wed Dec 12 00:00:00 EST 2018
Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation.
Journal of cell science
Nagai T,Mukoyama S,Kagiwada H,Goshima N,Mizuno K
Wed Dec 12 00:00:00 EST 2018