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CXCR1 Antibody (MA1-206) in ICC/IF
Immunofluorescent analysis of CXCR1/IL8RA (green) in MCF7 cells. Cells were blocked with blocking buffer (Product # 37525) for 30 min at room temparture and then stained with CXCR1/IL8RA mouse monoclonal antibody (Product # MA1-206) at a dilution of 1:100 for 1 hour at room temperature. After washing with PBS for 3 times, the cells were then stained with Alexa Fluor 488 goat anti-mouse secondary antibody (Product # A28175) for 1 hour at room temperature. The cells were fixed with 4% paraformaldehyde for 30 minutes at room temperature. Nucl... View More
产品信息
MA1-206
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
501
抗原
Synthetic peptide corresponding to the N-terminal residues 5-19 of human CXCR1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 1mg/mL BSA, 30% glycerol
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2637106
产品详细信息
MA1-206 detects CXCR1/IL8RA from human samples.
MA1-206 has been successfully tested in western blot, immunofluorescence and flow cytometry applications. In western blot, MA1-206 detects CXCR1/IL8RA (human) at approximate molecular weight of 30 kDa.
靶标信息
CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 1; CC motif chemokine; CCmotif chemokine; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CXC; CXC motif chemokine; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL-RA; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
基因别名: C-C; C-C-CKR-1; CD128; CD181; CDw128a; CKR-1; CMKAR1; CXCR1; IL8R1; IL8RA; IL8RBA
UniProt ID: (Human) P25024
Entrez Gene ID: (Human) 3577
