Product References
Synergistic effects of combined treatment of 1,2-dichloroethane and high-dose ethanol on liver damage in mice and the related mechanisms.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yang J,Zhang L,Wang T,Zhang J,Li M,Jin X,Tan X,Wang G,Zhao F,Jin Y
Thu Jun 01 00:00:00 EDT 2023
Synergistic effects of combined treatment of 1,2-dichloroethane and high-dose ethanol on liver damage in mice and the related mechanisms.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yang J,Zhang L,Wang T,Zhang J,Li M,Jin X,Tan X,Wang G,Zhao F,Jin Y
Thu Jun 01 00:00:00 EDT 2023
Integration of proteomics and network toxicology reveals the mechanism of mercury chloride induced hepatotoxicity, in mice and HepG2 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Cao X,Mao K,Zhang Y,Yang M,Liu H,Wang X,Hao L
Sat Jul 01 00:00:00 EDT 2023
Hydroxytyrosol attenuates ethanol-induced liver injury by ameliorating steatosis, oxidative stress and hepatic inflammation by interfering STAT3/iNOS pathway.
Redox report : communications in free radical research
Fang X,Cao J,Tao Z,Yang Z,Dai Y,Zhao L
Fri Dec 01 00:00:00 EST 2023
Hepatitis B virus X protein induces ALDH2 ubiquitin-dependent degradation to enhance alcoholic steatohepatitis.
Gastroenterology report
Zhou H,Wan S,Luo Y,Liu H,Jiang J,Guo Y,Xiao J,Wu B
Tue Mar 07 00:00:00 EST 2023
Autophagy and exosomes coordinately mediate quercetin's protective effects on alcoholic liver disease.
The Journal of nutritional biochemistry
Chen H,Liu J,Peng S,Yang G,Cheng X,Chen L,Zhang H,Zhao Y,Yao P,Tang Y
Thu Jun 01 00:00:00 EDT 2023
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Cell host & microbe
Zeng Y,Wu R,Wang F,Li S,Li L,Li Y,Qin P,Wei M,Yang J,Wu J,Chen A,Ke G,Yan Z,Yang H,Chen Z,Wang Z,Xiao W,Jiang Y,Chen X,Zeng Z,Zhao X,Chen P,Gong S
Wed May 10 00:00:00 EDT 2023
AFG1-induced TNF-α-mediated inflammation enhances gastric epithelial cell injury via CYP2E1.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wu X,Meng W,Duan C,Cao J,Wei Y,Cui X,Zhu D,Lv P,Shen H,Zhang X
Thu Jun 01 00:00:00 EDT 2023
Mitoquinone protects against acetaminophen-induced liver injury in an FSP1-dependent and GPX4-independent manner.
Toxicology and applied pharmacology
He X,Liang SM,Wang HQ,Tao L,Sun FF,Wang Y,Zhang C,Huang YC,Xu DX,Chen X
Sat Apr 15 00:00:00 EDT 2023
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Ecotoxicology and environmental safety
Liu F,Wang Y,Chen L,Bello BK,Zhang T,Yang H,Li X,Pan E,Feng H,Dong J
Sat Oct 01 00:00:00 EDT 2022
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Bioorganic chemistry
Li T,Chen Y,Tan P,Shi H,Huang Z,Cai T,Cheng Y,Du Y,Fu W
Sun May 01 00:00:00 EDT 2022
Cytochrome P450 2E1 predicts liver functional recovery from donation after circulatory death using air-ventilated normothermic machine perfusion.
Scientific reports
Shi JH,Yang DJ,Jin Q,Cheng N,Shi YB,Bai Y,Yu DS,Guo WZ,Ge GB,Zhang SJ
Fri May 06 00:00:00 EDT 2022
Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis.
Food research international (Ottawa, Ont.)
Ding Q,Cao F,Lai S,Zhuge H,Chang K,Valencak TG,Liu J,Li S,Ren D
Fri Jul 01 00:00:00 EDT 2022
Sinomenine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress, inflammation and apoptosis in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Fan H,Tu T,Zhang X,Yang Q,Liu G,Zhang T,Bao Y,Lu Y,Dong Z,Dong J,Zhao P
Sat Jan 01 00:00:00 EST 2022
Protecting mitochondria via inhibiting VDAC1 oligomerization alleviates ferroptosis in acetaminophen-induced acute liver injury.
Cell biology and toxicology
Niu B,Lei X,Xu Q,Ju Y,Xu D,Mao L,Li J,Zheng Y,Sun N,Zhang X,Mao Y,Li X
Wed Jun 01 00:00:00 EDT 2022
Periplaneta americana extract alleviates steatohepatitis in a mouse model by modulating HMGB1-mediated inflammatory response.
Frontiers in pharmacology
Xiao Y,Gao C,Wu J,Li J,Wang L,You Y,Peng T,Zhang K,Cao M,Hong J
Tue Oct 25 00:00:00 EDT 2022
Kinetic Characteristics of Curcumin and Germacrone in Rat and Human Liver Microsomes: Involvement of CYP Enzymes.
Molecules (Basel, Switzerland)
Su S,Wu H,Zhou J,Yuan G,Wang H,Feng J
Thu Jul 14 00:00:00 EDT 2022
Silymarin Protects against Acute Liver Injury Induced by Acetaminophen by Downregulating the Expression and Activity of the CYP2E1 Enzyme.
Molecules (Basel, Switzerland)
Yang W,Liang Z,Wen C,Jiang X,Wang L
Tue Dec 13 00:00:00 EST 2022
The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease.
Journal of experimental & clinical cancer research : CR
Cigliano A,Zhang S,Ribback S,Steinmann S,Sini M,Ament CE,Utpatel K,Song X,Wang J,Pilo MG,Berger F,Wang H,Tao J,Li X,Pes GM,Mancarella S,Giannelli G,Dombrowski F,Evert M,Calvisi DF,Chen X,Evert K
Fri Jun 03 00:00:00 EDT 2022
MicroRNA-29b ameliorates hepatic inflammation via suppression of STAT3 in alcohol-associated liver disease.
Alcohol (Fayetteville, N.Y.)
Zhou K,Yin F,Li Y,Ma C,Liu P,Xin Z,Ren R,Wei S,Khan M,Wang H,Zhang H
Tue Mar 01 00:00:00 EST 2022
Baicalin ameliorates alcohol-induced hepatic steatosis by suppressing SREBP1c elicited PNPLA3 competitive binding to ATGL.
Archives of biochemistry and biophysics
Li P,Chen Y,Ke X,Zhang R,Zuo L,Wang M,Chen Z,Luo X,Wang J
Wed Jun 15 00:00:00 EDT 2022
Egr1 confers protection against acetaminophen‑induced hepatotoxicity via transcriptional upregulating of Acaa2.
International journal of biological sciences
Lei X,Xu Q,Li C,Niu B,Ming Y,Li J,Tang Y,Li X,Tang J,Wu J,Ju Y,Yao L,Wang B,Miao Q,Zhong W,Zhi Y,Xu L,Li C,Li X,Mao Y
Tue Jul 12 00:00:00 EDT 2022
Kinsenoside Alleviates Alcoholic Liver Injury by Reducing Oxidative Stress, Inhibiting Endoplasmic Reticulum Stress, and Regulating AMPK-Dependent Autophagy.
Frontiers in pharmacology
Gao L,Chen X,Fu Z,Yin J,Wang Y,Sun W,Ren H,Zhang Y
Sat Feb 05 00:00:00 EST 2022
Compromised glutathione synthesis results in high susceptibility to acetaminophen hepatotoxicity in acatalasemic mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Ogino N,Nagaoka K,Tomizuka K,Matsuura-Harada Y,Eitoku M,Suganuma N,Ogino K
Fri Oct 01 00:00:00 EDT 2021
Allicin alleviated acrylamide-induced NLRP3 inflammasome activation via oxidative stress and endoplasmic reticulum stress in Kupffer cells and SD rats liver.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Nan B,Yang C,Li L,Ye H,Yan H,Wang M,Yuan Y
Mon Feb 01 00:00:00 EST 2021
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats.
Chemical research in toxicology
Tan B,Chen J,Qin S,Liao C,Zhang Y,Wang D,Li S,Zhang Z,Zhang P,Xu F
Mon Jul 19 00:00:00 EDT 2021
Effect of fucoidan on ethanol-induced liver injury and steatosis in mice and the underlying mechanism.
Food & nutrition research
Xue M,Liang H,Zhou Z,Liu Y,He X,Zhang Z,Sun T,Yang J,Qin Y,Qin K
Sat Nov 11 00:00:00 EST 2023
Effect of fucoidan on ethanol-induced liver injury and steatosis in mice and the underlying mechanism.
Food & nutrition research
Xue M,Liang H,Zhou Z,Liu Y,He X,Zhang Z,Sun T,Yang J,Qin Y,Qin K
Sat Nov 11 00:00:00 EST 2023
Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1.
Human & experimental toxicology
Jiang HY,Bao YN,Lin FM,Jin Y
Wed Dec 01 00:00:00 EST 2021
Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1.
Human & experimental toxicology
Jiang HY,Bao YN,Lin FM,Jin Y
Wed Dec 01 00:00:00 EST 2021
Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1.
Human & experimental toxicology
Jiang HY,Bao YN,Lin FM,Jin Y
Wed Dec 01 00:00:00 EST 2021
Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1.
Human & experimental toxicology
Jiang HY,Bao YN,Lin FM,Jin Y
Wed Dec 01 00:00:00 EST 2021
Integrated Analyses Identify Key Molecules and Reveal the Potential Mechanism of miR-182-5p/FOXO1 Axis in Alcoholic Liver Disease.
Frontiers in medicine
Zuo Z,Li Y,Zeng C,Xi Y,Tao H,Guo Y
Sat Dec 25 00:00:00 EST 2021
TA allele of rs2070673 in the CYP2E1 gene is associated with lobular inflammation and nonalcoholic steatohepatitis in patients with biopsy-proven nonalcoholic fatty liver disease.
Journal of gastroenterology and hepatology
Ma HL,Chen SD,Zheng KI,Yu Y,Wang XX,Tang LJ,Li G,Rios RS,Huang OY,Zheng XY,Xu RA,Targher G,Byrne CD,Wang XD,Chen YP,Zheng MH
Fri Oct 01 00:00:00 EDT 2021
Gut microbiota accelerates cisplatin-induced acute liver injury associated with robust inflammation and oxidative stress in mice.
Journal of translational medicine
Gong S,Feng Y,Zeng Y,Zhang H,Pan M,He F,Wu R,Chen J,Lu J,Zhang S,Yuan S,Chen X
Tue Apr 13 00:00:00 EDT 2021
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Food & function
Qu L,Fu R,Ma X,Fan D
Mon Oct 04 00:00:00 EDT 2021
Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhao L,Zhao J,Gao R,Tian Y,Zhang Y,Tang W,Jiang Y,Li C,Wang M,Yang F,Li G
Sun Mar 01 00:00:00 EST 2020
Intestinal Epithelial Chemokine (C-C Motif) Ligand 7 Overexpression Enhances Acetaminophen-Induced Hepatotoxicity in Mice.
The American journal of pathology
Niu M,Luo Z,Gong S,Win S,Kaplowitz N,Jiang Y,Chen P
Wed Jan 01 00:00:00 EST 2020
circ-CBFB upregulates p66Shc to perturb mitochondrial dynamics in APAP-induced liver injury.
Cell death & disease
Wang Z,Zhao Y,Sun R,Sun Y,Liu D,Lin M,Chen Z,Zhou J,Lv L,Tian X,Yao J
Fri Nov 06 00:00:00 EST 2020
Knockdown of Long Noncoding RNAs Hepatocyte Nuclear Factor 1α Antisense RNA 1 and Hepatocyte Nuclear Factor 4α Antisense RNA 1 Alters Susceptibility of Acetaminophen-Induced Cytotoxicity in HepaRG Cells.
Molecular pharmacology
Chen L,Wang P,Manautou JE,Zhong XB
Wed Apr 01 00:00:00 EDT 2020
Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways.
Life sciences
Li Z,Lian Y,Wei R,Jin L,Cao H,Zhao T,Ma X,Zhong M,Gao Y,Zhang K
Tue Dec 01 00:00:00 EST 2020
Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure.
Cell death & disease
Yamada N,Karasawa T,Kimura H,Watanabe S,Komada T,Kamata R,Sampilvanjil A,Ito J,Nakagawa K,Kuwata H,Hara S,Mizuta K,Sakuma Y,Sata N,Takahashi M
Mon Feb 24 00:00:00 EST 2020
Pyruvate Kinase M2 Tetramerization Protects against Hepatic Stellate Cell Activation and Liver Fibrosis.
The American journal of pathology
Zheng D,Jiang Y,Qu C,Yuan H,Hu K,He L,Chen P,Li J,Tu M,Lin L,Chen H,Lin Z,Lin W,Fan J,Cheng G,Hong J
Sun Nov 01 00:00:00 EDT 2020
Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of cytochrome P4502E1.
The Journal of biological chemistry
Chen L,Guo P,Zhang H,Li W,Gao C,Huang Z,Fan J,Zhang Y,Li X,Liu X,Wang F,Wang S,Li Q,He Z,Li H,Chen S,Wu X,Ye L,Li Q,Tang H,Wang Q,Dong G,Xiao Y,Chen W,Li D
Fri Feb 15 00:00:00 EST 2019
Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of cytochrome P4502E1.
The Journal of biological chemistry
Chen L,Guo P,Zhang H,Li W,Gao C,Huang Z,Fan J,Zhang Y,Li X,Liu X,Wang F,Wang S,Li Q,He Z,Li H,Chen S,Wu X,Ye L,Li Q,Tang H,Wang Q,Dong G,Xiao Y,Chen W,Li D
Fri Feb 15 00:00:00 EST 2019
Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of cytochrome P4502E1.
The Journal of biological chemistry
Chen L,Guo P,Zhang H,Li W,Gao C,Huang Z,Fan J,Zhang Y,Li X,Liu X,Wang F,Wang S,Li Q,He Z,Li H,Chen S,Wu X,Ye L,Li Q,Tang H,Wang Q,Dong G,Xiao Y,Chen W,Li D
Fri Feb 15 00:00:00 EST 2019
Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of cytochrome P4502E1.
The Journal of biological chemistry
Chen L,Guo P,Zhang H,Li W,Gao C,Huang Z,Fan J,Zhang Y,Li X,Liu X,Wang F,Wang S,Li Q,He Z,Li H,Chen S,Wu X,Ye L,Li Q,Tang H,Wang Q,Dong G,Xiao Y,Chen W,Li D
Fri Feb 15 00:00:00 EST 2019
Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae.
Cell metabolism
Yuan J,Chen C,Cui J,Lu J,Yan C,Wei X,Zhao X,Li N,Li S,Xue G,Cheng W,Li B,Li H,Lin W,Tian C,Zhao J,Han J,An D,Zhang Q,Wei H,Zheng M,Ma X,Li W,Chen X,Zhang Z,Zeng H,Ying S,Wu J,Yang R,Liu D
Tue Oct 01 00:00:00 EDT 2019
Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway.
The American journal of Chinese medicine
Zhou X,Xiong J,Lu S,Luo L,Chen ZL,Yang F,Jin F,Wang Y,Ma Q,Luo YY,Wang YJ,Zhou JB,Liu P,Zhao L
Fri Apr 03 00:00:00 EDT 2020
Hepatoprotective Potential of Partially Hydrolyzed Guar Gum against Acute Alcohol-Induced Liver Injury in Vitro and Vivo.
Nutrients
Wu C,Liu J,Tang Y,Li Y,Yan Q,Jiang Z
Sat Apr 27 00:00:00 EDT 2019
Chronic intake of high-dose of blueberry leaf extract does not augment the harmful effects of ethanol in rats.
PeerJ
Yamasaki K,Sugamoto K,Arakawa T,Nishiyama K,Yamasaki M
Thu Oct 12 00:00:00 EDT 2023
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Qu L,Zhu Y,Liu Y,Yang H,Zhu C,Ma P,Deng J,Fan D
Mon Apr 01 00:00:00 EDT 2019
CCl4-Induced Liver Injury Was Ameliorated by Qi-Ge Decoction through the Antioxidant Pathway.
Evidence-based complementary and alternative medicine : eCAM
Peng C,Zhou ZM,Li J,Luo Y,Zhou YS,Ke XH,Huang KE
Wed Sep 30 00:00:00 EDT 2020
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Thu Aug 01 00:00:00 EDT 2019
Inhibition of the mitochondrial complex-1 protects against carbon tetrachloride-induced acute liver injury.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hua H,Zhang Z,Qian Y,Yuan H,Ge W,Huang S,Zhang A,Zhang Y,Jia Z,Ding G
Mon Jul 01 00:00:00 EDT 2019
Neuroprotective Effect of Dioscin on the Aging Brain.
Molecules (Basel, Switzerland)
Qi Y,Li R,Xu L,Yin L,Xu Y,Han X,Peng J
Sat Mar 30 00:00:00 EDT 2019
Salvianolic acid A alleviates chronic ethanol-induced liver injury via promotion of β-catenin nuclear accumulation by restoring SIRT1 in rats.
Toxicology and applied pharmacology
Shi X,Zhao Y,Ding C,Wang Z,Ji A,Li Z,Feng D,Li Y,Gao D,Zhou J,Tian X,Yao J
Sun Jul 01 00:00:00 EDT 2018
Salvianolic acid A alleviates chronic ethanol-induced liver injury via promotion of β-catenin nuclear accumulation by restoring SIRT1 in rats.
Toxicology and applied pharmacology
Shi X,Zhao Y,Ding C,Wang Z,Ji A,Li Z,Feng D,Li Y,Gao D,Zhou J,Tian X,Yao J
Sun Jul 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Regulatory toxicology and pharmacology : RTP
Ning C,Gao X,Wang C,Kong Y,Liu Z,Sun H,Sun P,Huo X,Ma X,Meng Q,Liu K
Mon Oct 01 00:00:00 EDT 2018
Decreased expression of hepatic cytochrome P450 1A2 (CYP1A2) in a chronic intermittent hypoxia mouse model.
Journal of thoracic disease
Zhang XB,Zeng YM,Chen XY,Zhang YX,Ding JZ,Xue C
Thu Feb 01 00:00:00 EST 2018
Decreased expression of hepatic cytochrome P450 1A2 (CYP1A2) in a chronic intermittent hypoxia mouse model.
Journal of thoracic disease
Zhang XB,Zeng YM,Chen XY,Zhang YX,Ding JZ,Xue C
Thu Feb 01 00:00:00 EST 2018
Schisantherin A alleviated alcohol-induced liver injury by the regulation of alcohol metabolism and NF-kB pathway.
Experimental animals
Li B,Li D,Wang Y,Meng X,Sun X,Tian J,Shi L,Ma F
Thu Nov 01 00:00:00 EDT 2018
Schisantherin A alleviated alcohol-induced liver injury by the regulation of alcohol metabolism and NF-kB pathway.
Experimental animals
Li B,Li D,Wang Y,Meng X,Sun X,Tian J,Shi L,Ma F
Thu Nov 01 00:00:00 EDT 2018
Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.
Cell death & disease
Wang C,Xu W,Zhang Y,Huang D,Huang K
Thu Jul 26 00:00:00 EDT 2018
Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.
Cell death & disease
Wang C,Xu W,Zhang Y,Huang D,Huang K
Thu Jul 26 00:00:00 EDT 2018
Neurotoxicity, behavioral changes and gene-expression profile of mice exposed to SnS2 nanoflowers.
Toxicology research
Bai D,Li Q,Wang J,Zhao J,Deng X,Yuan L,Wu P
Thu Nov 01 00:00:00 EDT 2018
Study on the potential way of hepatic cytotoxicity of N,N-dimethylformamide.
Journal of biochemical and molecular toxicology
Li S,Wang C
Sat Sep 01 00:00:00 EDT 2018
Liver-specific deficiency of unc-51 like kinase 1 and 2 protects mice from acetaminophen-induced liver injury.
Hepatology (Baltimore, Md.)
Sun Y,Li TY,Song L,Zhang C,Li J,Lin ZZ,Lin SC,Lin SY
Fri Jun 01 00:00:00 EDT 2018
Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice.
Oxidative medicine and cellular longevity
Wu H,Zhang G,Huang L,Pang H,Zhang N,Chen Y,Wang G
Mon Mar 19 00:00:00 EDT 2018
Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice.
Oxidative medicine and cellular longevity
Wu H,Zhang G,Huang L,Pang H,Zhang N,Chen Y,Wang G
Mon Mar 19 00:00:00 EDT 2018
Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice.
International immunopharmacology
Yang G,Zhang L,Ma L,Jiang R,Kuang G,Li K,Tie H,Wang B,Chen X,Xie T,Gong X,Wan J
Fri Sep 01 00:00:00 EDT 2017
Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice.
International immunopharmacology
Yang G,Zhang L,Ma L,Jiang R,Kuang G,Li K,Tie H,Wang B,Chen X,Xie T,Gong X,Wan J
Fri Sep 01 00:00:00 EDT 2017
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
International journal of molecular medicine
Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H
Sat Apr 01 00:00:00 EDT 2017
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
International journal of molecular medicine
Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H
Sat Apr 01 00:00:00 EDT 2017
Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene expression.
Chemico-biological interactions
Wang F,Liu JC,Zhou RJ,Zhao X,Liu M,Ye H,Xie ML
Mon Sep 25 00:00:00 EDT 2017
Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene expression.
Chemico-biological interactions
Wang F,Liu JC,Zhou RJ,Zhao X,Liu M,Ye H,Xie ML
Mon Sep 25 00:00:00 EDT 2017
Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions†.
Biology of reproduction
Katen AL,Sipilä P,Mitchell LA,Stanger SJ,Nixon B,Roman SD
Sat Apr 01 00:00:00 EDT 2017
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
Clinical nutrition (Edinburgh, Scotland)
Shi H,Shi A,Dong L,Lu X,Wang Y,Zhao J,Dai F,Guo X
Thu Dec 01 00:00:00 EST 2016
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
Clinical nutrition (Edinburgh, Scotland)
Shi H,Shi A,Dong L,Lu X,Wang Y,Zhao J,Dai F,Guo X
Thu Dec 01 00:00:00 EST 2016
Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat.
World journal of gastroenterology
Jiang W,Guo MH,Hai X
Wed Dec 14 00:00:00 EST 2016
Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat.
World journal of gastroenterology
Jiang W,Guo MH,Hai X
Wed Dec 14 00:00:00 EST 2016
Chronic plus binge ethanol exposure causes more severe pancreatic injury and inflammation.
Toxicology and applied pharmacology
Ren Z,Yang F,Wang X,Wang Y,Xu M,Frank JA,Ke ZJ,Zhang Z,Shi X,Luo J
Sat Oct 01 00:00:00 EDT 2016
Chronic plus binge ethanol exposure causes more severe pancreatic injury and inflammation.
Toxicology and applied pharmacology
Ren Z,Yang F,Wang X,Wang Y,Xu M,Frank JA,Ke ZJ,Zhang Z,Shi X,Luo J
Sat Oct 01 00:00:00 EDT 2016
Chronic Acrylamide Exposure in Male Mice Results in Elevated DNA Damage in the Germline and Heritable Induction of CYP2E1 in the Testes.
Biology of reproduction
Katen AL,Chambers CG,Nixon B,Roman SD
Sat Oct 01 00:00:00 EDT 2016
Chronic Acrylamide Exposure in Male Mice Results in Elevated DNA Damage in the Germline and Heritable Induction of CYP2E1 in the Testes.
Biology of reproduction
Katen AL,Chambers CG,Nixon B,Roman SD
Sat Oct 01 00:00:00 EDT 2016
Chronic Acrylamide Exposure in Male Mice Results in Elevated DNA Damage in the Germline and Heritable Induction of CYP2E1 in the Testes.
Biology of reproduction
Katen AL,Chambers CG,Nixon B,Roman SD
Sat Oct 01 00:00:00 EDT 2016
Chronic Acrylamide Exposure in Male Mice Results in Elevated DNA Damage in the Germline and Heritable Induction of CYP2E1 in the Testes.
Biology of reproduction
Katen AL,Chambers CG,Nixon B,Roman SD
Sat Oct 01 00:00:00 EDT 2016
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Nutrients
Dong D,Yin L,Qi Y,Xu L,Peng J
Mon Jun 15 00:00:00 EDT 2015
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Nutrients
Dong D,Yin L,Qi Y,Xu L,Peng J
Mon Jun 15 00:00:00 EDT 2015
Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR.
Toxins
Zhang B,Liu Y,Li X
Mon Mar 30 00:00:00 EDT 2015
Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR.
Toxins
Zhang B,Liu Y,Li X
Mon Mar 30 00:00:00 EDT 2015
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Protective effects of dioscin against alcohol-induced liver injury.
Archives of toxicology
Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J
Sat Mar 01 00:00:00 EST 2014
Protective effects of dioscin against alcohol-induced liver injury.
Archives of toxicology
Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J
Sat Mar 01 00:00:00 EST 2014
Protective effects of dioscin against alcohol-induced liver injury.
Archives of toxicology
Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J
Sat Mar 01 00:00:00 EST 2014
Ursolic acid protects mouse liver against CCl4-induced oxidative stress and inflammation by the MAPK/NF-κB pathway.
Environmental toxicology and pharmacology
Ma JQ,Ding J,Zhang L,Liu CM
Thu May 01 00:00:00 EDT 2014
Ursolic acid protects mouse liver against CCl4-induced oxidative stress and inflammation by the MAPK/NF-κB pathway.
Environmental toxicology and pharmacology
Ma JQ,Ding J,Zhang L,Liu CM
Thu May 01 00:00:00 EDT 2014
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
International immunopharmacology
Yu H,Zheng L,Yin L,Xu L,Qi Y,Han X,Xu Y,Liu K,Peng J
Tue Apr 01 00:00:00 EDT 2014
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
International immunopharmacology
Yu H,Zheng L,Yin L,Xu L,Qi Y,Han X,Xu Y,Liu K,Peng J
Tue Apr 01 00:00:00 EDT 2014
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
International immunopharmacology
Yu H,Zheng L,Yin L,Xu L,Qi Y,Han X,Xu Y,Liu K,Peng J
Tue Apr 01 00:00:00 EDT 2014
Protective effects of the total saponins from Dioscorea nipponica Makino against carbon tetrachloride-induced liver injury in mice through suppression of apoptosis and inflammation.
International immunopharmacology
Yu H,Zheng L,Yin L,Xu L,Qi Y,Han X,Xu Y,Liu K,Peng J
Tue Apr 01 00:00:00 EDT 2014
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
Transplantation
Tao X,Wan X,Xu Y,Xu L,Qi Y,Yin L,Han X,Lin Y,Peng J
Sat Sep 27 00:00:00 EDT 2014
Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis.
Transplantation
Tao X,Wan X,Xu Y,Xu L,Qi Y,Yin L,Han X,Lin Y,Peng J
Sat Sep 27 00:00:00 EDT 2014
Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals
Lee JK,Chung HJ,Fischer L,Fischer J,Gonzalez FJ,Jeong H
Tue Apr 01 00:00:00 EDT 2014
Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals
Lee JK,Chung HJ,Fischer L,Fischer J,Gonzalez FJ,Jeong H
Tue Apr 01 00:00:00 EDT 2014
Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.
Molecules (Basel, Switzerland)
Liu M,Xu Y,Han X,Liang C,Yin L,Xu L,Qi Y,Zhao Y,Peng J,Sun C
Thu Aug 07 00:00:00 EDT 2014
Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.
Molecules (Basel, Switzerland)
Liu M,Xu Y,Han X,Liang C,Yin L,Xu L,Qi Y,Zhao Y,Peng J,Sun C
Thu Aug 07 00:00:00 EDT 2014
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Food chemistry
Zhang S,Zheng L,Dong D,Xu L,Yin L,Qi Y,Han X,Lin Y,Liu K,Peng J
Sun Dec 01 00:00:00 EST 2013
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Food chemistry
Zhang S,Zheng L,Dong D,Xu L,Yin L,Qi Y,Han X,Lin Y,Liu K,Peng J
Sun Dec 01 00:00:00 EST 2013
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Food chemistry
Zhang S,Zheng L,Dong D,Xu L,Yin L,Qi Y,Han X,Lin Y,Liu K,Peng J
Sun Dec 01 00:00:00 EST 2013
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Food chemistry
Zhang S,Zheng L,Dong D,Xu L,Yin L,Qi Y,Han X,Lin Y,Liu K,Peng J
Sun Dec 01 00:00:00 EST 2013
Protection of cyanidin-3-glucoside against oxidative stress induced by acrylamide in human MDA-MB-231 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Song J,Zhao M,Liu X,Zhu Y,Hu X,Chen F
Thu Aug 01 00:00:00 EDT 2013
Protection of cyanidin-3-glucoside against oxidative stress induced by acrylamide in human MDA-MB-231 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Song J,Zhao M,Liu X,Zhu Y,Hu X,Chen F
Thu Aug 01 00:00:00 EDT 2013
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dong D,Zhang S,Yin L,Tang X,Xu Y,Han X,Qi Y,Peng J
Sun Dec 01 00:00:00 EST 2013
Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dong D,Zhang S,Yin L,Tang X,Xu Y,Han X,Qi Y,Peng J
Sun Dec 01 00:00:00 EST 2013
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.
Toxicology letters
Zhao X,Cong X,Zheng L,Xu L,Yin L,Peng J
Tue Oct 02 00:00:00 EDT 2012
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.
Toxicology letters
Zhao X,Cong X,Zheng L,Xu L,Yin L,Peng J
Tue Oct 02 00:00:00 EDT 2012
Protective effect of L-theanine on carbon tetrachloride-induced acute liver injury in mice.
Biochemical and biophysical research communications
Jiang W,Gao M,Sun S,Bi A,Xin Y,Han X,Wang L,Yin Z,Luo L
Fri Jun 01 00:00:00 EDT 2012
Protective effect of L-theanine on carbon tetrachloride-induced acute liver injury in mice.
Biochemical and biophysical research communications
Jiang W,Gao M,Sun S,Bi A,Xin Y,Han X,Wang L,Yin Z,Luo L
Fri Jun 01 00:00:00 EDT 2012
