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NeoBiotechnologies
Calretinin/Calbindin 2 (Mesothelioma Marker) Recombinant Rabbit Monoclonal Antibody (CALB2/7029R)
产品信息
794-RBM12-P1
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
CALB2/7029R
抗原
Recombinant human Calretinin (Calbindin 2) protein fragment (around aa23-242).
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Antibody is stable for 24 months.
Positive Control: Human brain, testis or mesothelioma tissue. Cellular Localization: Cytoplasm. Nucleus.
Specificity Comments: It recognizes a protein of about 29kDa, which is identified as Calretinin (also known as Calbindin 2). Calretinin is a vitamin D-dependent calcium-binding protein involved in calcium signaling. It is present in subsets of neurons throughout the brain and spinal chord, including sensory ganglia. Antibody to calretinin is useful in differentiating mesothelioma from adeno carcinomas of the lung. It also aids in differentiating adrenal cortical neoplasms from pheochromocytomas.
靶标信息
Calretinin is encoded by the CALB2 gene located on chromosome 16. It is a troponin C superfamily protein having six EF-hand structural motifs. The EF motif allows the protein to bind calcium, and function in calcium signaling, calcium buffering, and modulating neuronal excitability. Calretinin is expressed in the mesothelium, mast cells, some neural cells, hair follicles, and fat cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 29 kDa calbindin; 29kD calretinin; 29kDa calbindin; calbindin 2, (29kD, calretinin); calbindin D29K; Calretinin; CR; testicular secretory protein Li 8
基因别名: CAB29; CAL2; CALB2; CR
UniProt ID: (Human) P22676
Entrez Gene ID: (Human) 794
