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Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Mouse, Rat, Hamster, Panda, Dog, Bat, Cat, Horse (100%).
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB-R; CB1; CB1 receptor; central cannabinoid receptor; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1; striatal cannabinoid receptor type 1 protein
基因别名: CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR; CNR1; I79_000677; Skr6; SKR6R
UniProt ID: (Human) P21554, (Mouse) P47746, (Rat) P20272
Entrez Gene ID: (Human) 1268, (Horse) 100065681, (Dog) 481913, (Mouse) 12801, (Chinese hamster) 100768005, (Rat) 25248