Invitrogen

Carboxypeptidase A1 Polyclonal Antibody

Carboxypeptidase A1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Carboxypeptidase A1 Antibody (PA5-86974) in IHC (P)

Immunohistochemical analysis of Carboxypeptidase A1 in paraffin-embedded human colon. Sample was incubated with Carboxypeptidase A1 polyclonal antibody (Product # PA5-86974) using a 1:100 dilution. Images are presented at 40x magnification.

Carboxypeptidase A1 Antibody in Western Blot (WB)

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产品信息

PA5-86974

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:100

免疫细胞化学 (ICC/IF)

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide of human CPA1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2803730

产品详细信息

Purity is > 95% by SDS-PAGE.

靶标信息

CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.

仅用于科研。不用于诊断过程。未经明确授权不得转售。