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Invitrogen
Cardiac Troponin C Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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Cardiac Troponin C Antibody (PA5-83741)
Relative expression in different tissues in IHC: Detection of differential expression levels of Cardiac Troponin C demonstrates antibody specificity. Immunohistochemical analysis of Cardiac Troponin C using anti-Cardiac Troponin C Polyclonal Antibody (Product #PA5-83741), shows significant staining of Cardiac Troponin C in heart muscle and shows minimal or weak staining in prostate tissues. The relative ex... View More
产品信息
PA5-83741
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.30 mg/mL
纯化类型
Anitgen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2790893
产品详细信息
Immunogen sequence: MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVM
靶标信息
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiac 3; cardiac troponin C; CMD1FF; CMD2A; CMH7; MGC116817; RCM1; slow twitch skeletal/cardiac muscle troponin C; TN-C; Tn1; Tni; TNN I3; TNNC 1; TNNI3; troponin C type 1 (slow); Troponin C, slow skeletal and cardiac muscles; troponin C1, slow; Troponin I cardiac; TroponinI
基因别名: CMD1Z; CMH13; TN-C; TNC; TNNC; TNNC1
UniProt ID: (Human) P63316
Entrez Gene ID: (Human) 7134
diaphragm contraction
skeletal muscle contraction
regulation of muscle contraction
response to metal ion
transition between fast and slow fiber
muscle filament sliding
regulation of muscle filament sliding speed
regulation of ATPase activity
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
