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产品信息
PA5-95994
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human TNNC1 (NP_0032711)
偶联物
形式
Liquid
浓度
0.68 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2807796
产品详细信息
Immunogen sequence: MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVMRMLGQ NPTPEELQEM IDEVDEDGSG TVDFDEFLVM MVRCMKDDSK GKSEEELSDL FRMFDKNADG YIDLDELKIM LQATGETITE DDIEELMKDG DKNNDGRIDY DEFLEFMKGV; Positive Samples: Mouse heart, Mouse lung, Mouse skeletal muscle
靶标信息
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cardiac 3; CMD1FF; CMD2A; CMH7; MGC116817; RCM1; TN-C; Tn1; Tni; TNN I3; TNNC 1; TNNI3; troponin C, cardiac/slow skeletal; Troponin C, slow skeletal and cardiac muscles; Troponin I cardiac; TroponinI
基因别名: AI874626; cTnC; cTnI; TnC; Tncc; Tnnc1
UniProt ID: (Mouse) P19123
Entrez Gene ID: (Rat) 290561, (Mouse) 21924
