Invitrogen

Catalase Polyclonal Antibody

高级验证

This Antibody was verified by Independent antibody to ensure that the antibody binds to the antigen stated.

1个已发表图片

4 篇参考文献

查看其他28个Catalase抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

Catalase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 9

Catalase Antibody (PA5-29183) in IHC (P)

Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Catalase (Product # PA5-29183) antibody at 1:500 dilution. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.

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产品信息

PA5-29183

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

查看3篇已发表文章 3篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 15 and 292 of Human Catalase

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.47 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol, 1% BSA

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2546659

产品详细信息

Recommended positive controls: CAT-transfected 293T, mouse kidney, rat kidney.

Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (88%), Drosophila (80%), Dog (97%), Pig (96%), Chicken (91%), Bovine (96%), Guinea pig (94%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

β-Nicotinamide Mononucleotide (NMN) Administrated by Intraperitoneal Injection Mediates Protection Against UVB-Induced Skin Damage in Mice.

Journal of inflammation research

Zhou X,Du HH,Long X,Pan Y,Hu J,Yu J,Zhao X

Published figure using Catalase polyclonal antibody (Product # PA5-29183) in Western Blot

Wed Apr 27 00:00:00 EDT 2022

PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult.

Molecular neurobiology

Cabezas R,Vega-Vela NE,González-Sanmiguel J,González J,Esquinas P,Echeverria V,Barreto GE

PA529183 was used in western blot to discuss mechanisms associated with platelet-derived growth factor, subtype BB protection against oxidative damage

Sun Apr 01 00:00:00 EDT 2018

Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction.

World journal of gastroenterology

Boland ML,Oldham S,Boland BB,Will S,Lapointe JM,Guionaud S,Rhodes CJ,Trevaskis JL

PA5-29183 was used in Immunohistochemistry to show the link between oxidative stress and/or capacity to compensate for increased oxidative stress and the development of hepatic injury and fibrosis in a state of mitochondrial dysfunction.

Sat Apr 28 00:00:00 EDT 2018

Ketogenic diet regulates the antioxidant catalase via the transcription factor PPARγ2.

Epilepsy research

Knowles S,Budney S,Deodhar M,Matthews SA,Simeone KA,Simeone TA

PA5-29183 was used in Western Blotting to propose catalase may contribute to ketogenic diet antiseizure efficacy and the diet can modulate its expression via PPARγ2 activation.