Product References
Prognostic value of HMGA2, CDK4, and JUN amplification in well-differentiated and dedifferentiated liposarcomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Saâda-Bouzid E,Burel-Vandenbos F,Ranchère-Vince D,Birtwisle-Peyrottes I,Chetaille B,Bouvier C,Château MC,Peoc'h M,Battistella M,Bazin A,Gal J,Michiels JF,Coindre JM,Pedeutour F,Bianchini L
MA5-13498 was used in immunohistochemistry to investigate the frequency and contribution of HMGA2, CDK4, and JUN to dedifferentiated liposarcomas and atypical lipomatous tumors/well-differentiated liposarcomas.
Sun Nov 01 00:00:00 UTC 2015
Myxoid liposarcoma with heterologous components: dedifferentiation or metaplasia? A FISH-documented and CGH-documented case report.
Applied immunohistochemistry & molecular morphology : AIMM
Weingertner N,Neuville A,Chibon F,Ray-Coquard I,Marcellin L,Ghnassia JP
MA5-13498 was used in immunohistochemistry - paraffin section to characterize a primary myxoid liposarcoma with chondroid and osseous components
Sun Mar 01 00:00:00 UTC 2015
Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess.
International journal of surgical pathology
Lee PW,Yau DT,Lau PP,Chan JK
MA5-13498 was used in immunohistochemistry to report on a case of plexiform fibromyxoma of the stomach.
Thu May 01 00:00:00 UTC 2014
Well-differentiated and dedifferentiated liposarcomas with prominent myxoid stroma: analysis of 56 cases.
Histopathology
Sioletic S,Dal Cin P,Fletcher CD,Hornick JL
MA5-13498 was used in immunohistochemistry to study the clinicopathological and genetic features of well-differentiated/dedifferentiated liposarcoma with prominent myxoid stroma.
Tue Jan 01 00:00:00 UTC 2013
The APC/C activator Cdh1 regulates the G2/M transition during differentiation of placental trophoblast stem cells.
Biochemical and biophysical research communications
Naoe H,Chiyoda T,Ishizawa J,Masuda K,Saya H,Kuninaka S
MA5-13498 was used in western blot to study the role of Cdh1 in regulating G2/M transition during placental differentiation
Fri Jan 11 00:00:00 UTC 2013
Incidental lipoma-like hibernoma arising from the adrenal gland: a well-differentiated liposarcoma mimicker.
Pathology, research and practice
Val-Bernal JF,Azueta A,Ortiz-Rivas LA,Fuentes J,Ballestero R
MA5-13498 was used in immunohistochemistry to describe a woman showing an incidental hibernoma associated with a cortical adenoma producing primary hyperaldosteronism.
Sun Dec 01 00:00:00 UTC 2013
Sensitivity of MDM2 amplification and unexpected multiple faint alphoid 12 (alpha 12 satellite sequences) signals in atypical lipomatous tumor.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Kashima T,Halai D,Ye H,Hing SN,Delaney D,Pollock R,O'Donnell P,Tirabosco R,Flanagan AM
MA5-13498 was used in immunohistochemistry to assess if MDM2 copy number distinguishes lipomas from atypical lipomatous tumors.
Mon Oct 01 00:00:00 UTC 2012
MDM2 and CDK4 immunohistochemical coexpression in high-grade osteosarcoma: correlation with a dedifferentiated subtype.
The American journal of surgical pathology
Yoshida A,Ushiku T,Motoi T,Beppu Y,Fukayama M,Tsuda H,Shibata T
MA5-13498 was used in immunohistochemistry (paraffin) to discuss markers that distinguish between different subtypes of osteosarcomas.
Thu Mar 01 00:00:00 UTC 2012
MDM2 and CDK4 immunohistochemistry is a valuable tool in the differential diagnosis of low-grade osteosarcomas and other primary fibro-osseous lesions of the bone.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Dujardin F,Binh MB,Bouvier C,Gomez-Brouchet A,Larousserie F,Muret Ad,Louis-Brennetot C,Aurias A,Coindre JM,Guillou L,Pedeutour F,Duval H,Collin C,de Pinieux G
MA5-13498 was used in immunohistochemistry to examine expression of MDM2-CDK4 in low-grade osteosarcomas and fibrous or fibro-osseous lesions of the bone or paraosseous soft tissue.
Sun May 01 00:00:00 UTC 2011
Malignant fat-forming solitary fibrous tumor (so-called "lipomatous hemangiopericytoma"): clinicopathologic analysis of 14 cases.
The American journal of surgical pathology
Lee JC,Fletcher CD
MA5-13498 was used in immunocytochemistry to characterize malignant fat-forming solitary fibrous tumor.
Mon Aug 01 00:00:00 UTC 2011
Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity.
Molecular and cellular biology
James MK,Ray A,Leznova D,Blain SW
MA5-13498 was used in immunoprecipitation to study if the growth state-dependent tyrosine phosphorylation of p27Kip1 determines whether or not it inhibits cdk4
Tue Jan 01 00:00:00 UTC 2008
Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.
Molecular biology of the cell
Rocha AS,Paternot S,Coulonval K,Dumont JE,Soares P,Roger PP
MA5-13498 was used in immunoprecipitation to study the role of CDK4 phosphorylation in the mechanism by which cAMP inhibits thyroid carcinoma cell proliferation
Sat Nov 01 00:00:00 UTC 2008
The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development.
Cancer research
Landis MW,Brown NE,Baker GL,Shifrin A,Das M,Geng Y,Sicinski P,Hinds PW
MA5-13498 was used in western blot to study whether the LxCxE domain of cyclin D1 which interacts with the retinoblastoma protein is required for normal murine development
Wed Aug 15 00:00:00 UTC 2007
Requirement for CDK4 kinase function in breast cancer.
Cancer cell
Yu Q,Sicinska E,Geng Y,Ahnström M,Zagozdzon A,Kong Y,Gardner H,Kiyokawa H,Harris LN,Stål O,Sicinski P
MA5-13498 was used in immunoprecipitation to study the importance of cyclin D1-dependent Cdk4 kinase activity in mammary tumorigenesis
Sun Jan 01 00:00:00 UTC 2006
In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202.
Clinical cancer research : an official journal of the American Association for Cancer Research
Raynaud FI,Whittaker SR,Fischer PM,McClue S,Walton MI,Barrie SE,Garrett MD,Rogers P,Clarke SJ,Kelland LR,Valenti M,Brunton L,Eccles S,Lane DP,Workman P
MA5-13498 was used in western blot to study the pharmacokinetics and pharmacodynamics of three tri-substituted aminopurine Cdk inhibitors in a model of colon carcinoma
Fri Jul 01 00:00:00 UTC 2005
p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2.
The Journal of cell biology
Rodier G,Makris C,Coulombe P,Scime A,Nakayama K,Nakayama KI,Meloche S
MA5-13498 was used in western blot to study the role of Skp2 in the mechanism by which p107 inhibits G1/S phase progression
Mon Jan 03 00:00:00 UTC 2005
Inflammatory malignant fibrous histiocytomas and dedifferentiated liposarcomas: histological review, genomic profile, and MDM2 and CDK4 status favour a single entity.
The Journal of pathology
Coindre JM,Hostein I,Maire G,Derré J,Guillou L,Leroux A,Ghnassia JP,Collin F,Pedeutour F,Aurias A
MA5-13498 was used in immunohistochemistry (frozen) to characterize dedifferentiated liposarcomas with an inflammatory malignant fibrous histiocytoma component.
Thu Jul 01 00:00:00 UTC 2004
Most malignant fibrous histiocytomas developed in the retroperitoneum are dedifferentiated liposarcomas: a review of 25 cases initially diagnosed as malignant fibrous histiocytoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Coindre JM,Mariani O,Chibon F,Mairal A,De Saint Aubain Somerhausen N,Favre-Guillevin E,Bui NB,Stoeckle E,Hostein I,Aurias A
MA5-13498 was used in immunohistochemistry (paraffin) to report that most so-called malignant fibrous histiocytomas from the retroperitoneum are dedifferentiated liposarcoma.
Sat Mar 01 00:00:00 UTC 2003
Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth.
American journal of physiology. Gastrointestinal and liver physiology
Ilyin GP,Glaise D,Gilot D,Baffet G,Guguen-Guillouzo C
MA5-13498 was used in western blot to study the role of the p21 and p27 cyclin-dependent kinase inhibitors in hepatocyte development and proliferation
Tue Jul 01 00:00:00 UTC 2003
Interaction of Hsp90 with the nascent form of the mutant epidermal growth factor receptor EGFRvIII.
The Journal of biological chemistry
Lavictoire SJ,Parolin DA,Klimowicz AC,Kelly JF,Lorimer IA
MA5-13498 was used in western blot to study the interaction of nascent EGFRvIII with Hsp90 and its importance for maintaining EGFRvIII expression
Fri Feb 14 00:00:00 UTC 2003
Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity.
Molecular and cellular biology
Tsutsui T,Hesabi B,Moons DS,Pandolfi PP,Hansel KS,Koff A,Kiyokawa H
MA5-13498 was used in western blot to study the role of CDK4 in cell cycle regulation using targeted knockdown
Fri Oct 01 00:00:00 UTC 1999
