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产品信息
PA5-22925
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
An C-terminal synthetic peptide made to the human ChREBP protein sequence (between residues 800-852).
偶联物
激发/发射光谱
556/570 nm
查看光谱
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
50mM sodium borate
内含物
no preservative
保存条件
4° C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152105
产品详细信息
The target sequence has 83% sequence homology with mouse ChREBP.
靶标信息
ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose. This protein may have relevance to lipid metabolism, obesity, and type II diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHd14; carbohydrate response element binding protein; Carbohydrate-responsive element-binding protein; ChREBP; Class D basic helix-loop-helix protein 14; MLX interacting protein-like; MLX interacting protein-like beta; MLX interactor; MLX-interacting protein-like; putative hepatic transcription factor; Williams Beuren syndrome chromosome region 14; Williams-Beuren syndrome chromosomal region 14 protein; Williams-Beuren syndrome chromosomal region 14 protein homolog; Williams-Beuren syndrome chromosome region 14 homolog; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2; Williams-Beuren syndrome chromosome region 14 protein 3; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH
基因别名: BHLHD14; CHREBP; MIO; MLXIPL; MONDOB; WBSCR14; WS-bHLH
UniProt ID: (Human) Q9NP71, (Mouse) Q99MZ3, (Rat) Q8VIP2
Entrez Gene ID: (Human) 51085, (Mouse) 58805, (Rat) 171078
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
carbohydrate response element binding
protein homodimerization activity
protein heterodimerization activity
protein binding
protein kinase binding
sequence-specific DNA binding
protein dimerization activity
DNA-binding transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
anatomical structure morphogenesis
glucose mediated signaling pathway
negative regulation of peptidyl-serine phosphorylation
intracellular signal transduction
glucose homeostasis
positive regulation of fatty acid biosynthetic process
positive regulation of glycolytic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of lipid biosynthetic process
fatty acid homeostasis
triglyceride homeostasis
negative regulation of cell cycle arrest
cellular response to carbohydrate stimulus
negative regulation of oxidative phosphorylation
regulation of energy homeostasis
regulation of glycolytic process
transcription from RNA polymerase II promoter
response to glucose
cellular response to glucose stimulus
