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Application
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Coilin Antibody (MA5-35373) in WB
Western blot analysis of Coilin in extracts of various cell lines. Samples were incubated with Coilin Monoclonal antibody (Product # MA5-35373) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
MA5-35373
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC0785
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Coilin (P38432)
偶联物
Unconjugated
形式
Liquid
浓度
0.63 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2849274
产品详细信息
Immunogen sequence: MAASETVRLR LQFDYPPPAT PHCTAFWLLV DLNRCRVVTD LISLIRQRFG FSSGAFLGLY LEGGLLPPAE SARLVRDNDC LRVKLEERGV AENSVVISNG
靶标信息
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Coilin; coilin p80; nuclear phosphoprotein of Cajal body; p80; p80-coilin
基因别名: C79982; CLN80; COIL; p80; p80-coilin
UniProt ID: (Human) P38432
Entrez Gene ID: (Human) 8161, (Mouse) 12812
