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Recommended positive controls: chondrocyte tissue.
PA1-26206 is expected to cross react with most mammals due to sequence homology. This antibody shows negligable cross reactivity with the Collagens 1, 3, 4, 5, and 6.
COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha-1 type II collagen; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; CGA; chondrocalcin; Collagen 2; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen type II (Col2A1) gene, enhancer region; collagen, type II, alpha 1; MGC131516; pro-alpha 1(II); Procollagen II alpha 1; procollagen, type II, alpha 1; unnamed protein product
基因别名: ANFH; AOM; CB11; CG2A1A; COL11A3; COL2A1; COLLII; SEDC; STL1
UniProt ID: (Human) P02458, (Bovine) P02459, (Rat) P05539
Entrez Gene ID: (Human) 1280, (Bovine) 407142, (Rat) 25412