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The monoclonal antibody 8A/E6 recognizes mouse complement receptor type-1 related gene Y (Crry/p65), a type I membrane protein (MW 56-60 kDa).
This gene encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 amino acids. The encoded protein may play a role in tumor immune surveillance, which is unrelated to complement inhibition. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Complement component receptor 1-like protein; complement receptor related protein; Complement regulatory protein Crry; MGC129536; Protein p65
基因别名: Cr1l; Crry; Cry; Mcp; mCRY
UniProt ID: (Mouse) Q64735
Entrez Gene ID: (Mouse) 12946