Proteintech

Cyclin A2 Polyclonal Antibody

3 篇参考文献

查看其他23个Cyclin A2抗体

抗体检测数据 (2)

Cyclin A2 Antibody in Western Blot (WB)

Cyclin A2 Antibody in Western Blot (WB)

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Cyclin A2 Antibody (27242-1-AP) in WB

WB result of Cyclin A2 antibody (27242-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Cyclin A2 transfected HeLa cells.

Cyclin A2 Antibody in Western Blot (WB)

Cyclin A2 Antibody in Western Blot (WB)

Product Image Gallery

Cyclin A2 Antibody in Western Blot (WB) — WB result of Cyclin A2 antibody (27242-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-Cyclin A2 transfected HeLa cells.

Cyclin A2 Antibody in Western Blot (WB) — Various lysates were subjected to SDS PAGE followed by western blot with 27242-1-AP (Cyclin A2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

产品信息

27242-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

查看3篇已发表文章 3篇已发表文章

产品规格

种属反应

Human

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Cyclin A2 Fusion Protein Ag25666 (405-432 aa encoded by BC104783)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.37 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: AQQSIREKY KNSKYHGVSL LNPPETLNL (405-432 aa encoded by BC104783)

靶标信息

Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Morusin inhibits the growth of human colorectal cancer HCT116‑derived sphere‑forming cells via the inactivation of Akt pathway.

International journal of molecular medicine

Zhou Y,Li X,Ye M

Thu Apr 01 00:00:00 EDT 2021

Methylation of NRN1 is a novel synthetic lethal marker of PI3K-Akt-mTOR and ATR inhibitors in esophageal cancer.

Cancer science

Du W,Gao A,Herman JG,Wang L,Zhang L,Jiao S,Guo M

Thu Jul 01 00:00:00 EDT 2021

Adefovir dipivoxil sensitizes colon cancer cells to vemurafenib by disrupting the KCTD12-CDK1 interaction.

Cancer letters

Yang J,Xu WW,Hong P,Ye F,Huang XH,Hu HF,Zhang QH,Yan X,Li B,He QY

Sat Jun 01 00:00:00 EDT 2019

生物信息学

蛋白别名: Cyclin A; Cyclin-A; Cyclin-A2

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基因别名: CCN1; CCNA; CCNA2

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UniProt ID: (Human) P20248

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Entrez Gene ID: (Human) 890

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protein binding protein kinase binding kinase activator

参与通路

regulation of cyclin-dependent protein serine/threonine kinase activity mitotic nuclear division mitotic G2 DNA damage checkpoint Ras protein signal transduction viral process organ regeneration response to glucagon cellular response to platelet-derived growth factor stimulus cellular response to leptin stimulus positive regulation of transcription, DNA-templated positive regulation of fibroblast proliferation cell division cellular response to cocaine cellular response to luteinizing hormone stimulus cellular response to estradiol stimulus cellular response to hypoxia cellular response to nitric oxide cochlea development cellular response to insulin-like growth factor stimulus