Product References
The Pt(S-pr-thiosal)2 and BCL1 Leukemia Lymphoma: Antitumor Activity In Vitro and In Vivo.
International journal of molecular sciences
Silconi ZB,Rosic V,Benazic S,Radosavljevic G,Mijajlovic M,Pantic J,Ratkovic ZR,Radic G,Arsenijevic A,Milovanovic M,Arsenijevic N,Milovanovic J
MA5-14336 was used in Flow cytometry/Cell sorting to explore the potential antitumor activity of previously synthetized platinum(IV) complex with alkyl derivatives of thyosalicilc acid, PtCl2(S-pr-thiosal)2, toward murine BCL1 cells and to delineate possible mechanisms of action.
Sun Jul 24 00:00:00 UTC 2022
Bio-nanoparticle based therapeutic vaccine induces immunogenic response against triple negative breast cancer.
American journal of cancer research
Bai X,Zhou Y,Lin Q,Huang CK,Zhang S,Carlson RI,Ghanbari H,Sun B,Wands JR,Dong X
MA5-14336 was used in Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot to conclude that λ phage vaccine targeting a TAA (ASPH) combined with DOX successfully induces ICD and initiates CD8+ T cell-mediated antitumor immunity in breast tumors.
Fri Oct 22 00:00:00 UTC 2021
Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis.
Cell death and differentiation
Wang L,Tu Z,Liu C,Liu H,Kaldis P,Chen Z,Li W
MA5-14336 was used in Western Blotting to demonstrate that germ cell-specific knockout of a shelterin complex subunit, Trf1, results in arrest of spermatocytes at two different stages.
Fri Jun 01 00:00:00 UTC 2018
The organic ester O,O'-diethyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis.
Oncotarget
Jurisevic M,Arsenijevic A,Pantic J,Gajovic N,Milovanovic J,Milovanovic M,Poljarevic J,Sabo T,Vojvodic D,Radosavljevic GD,Arsenijevic N
MA5-14336 was used in Immunocytochemistry to examine the ability of DE-EDCP to inhibit 4T1 murine breast cancer growth and progression, and to explore possible molecular mechanisms.
Fri Jun 15 00:00:00 UTC 2018
Induction of apoptosis by Galectin-9 in liver metastatic cancer cells: In vitro study.
International journal of oncology
Tadokoro T,Fujihara S,Chiyo T,Oura K,Samukawa E,Yamana Y,Fujita K,Mimura S,Sakamoto T,Nomura T,Tani J,Yoneyama H,Morishita A,Himoto T,Iwama H,Niki T,Hirashima M,Masaki T
MA5-14336 was used in Western Blotting to reveal that Gal-9 suppresses the growth of liver metastasis, possibly by inducing apoptosis through a mechanism involving mitochondria and changes in miRNA expression.
Tue Aug 01 00:00:00 UTC 2017
Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1.
The Journal of biological chemistry
Pozner A,Terooatea TW,Buck-Koehntop BA
MA514336 was used in western blot to investigate ZBTB33 modulation of the cyclin D1/cyclin E1/RB1/E2F pathway
Fri Nov 18 00:00:00 UTC 2016
Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1.
The Journal of biological chemistry
Pozner A,Terooatea TW,Buck-Koehntop BA
MA514336 was used in western blot to investigate ZBTB33 modulation of the cyclin D1/cyclin E1/RB1/E2F pathway
Fri Nov 18 00:00:00 UTC 2016
Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients.
Oncotarget
Duchnowska R,Wysocki PJ,Korski K,Czartoryska-Arłukowicz B,Niwińska A,Orlikowska M,Radecka B,Studziński M,Demlova R,Ziółkowska B,Merdalska M,Hajac Ł,Myśliwiec P,Zuziak D,Dębska-Szmich S,Lang I,Foszczyńska-Kłoda M,Karczmarek-Borowska B,Żawrocki A,Kowalczyk A,Biernat W,Jassem J
MA5-14336 was used in immunohistochemistry - paraffin section to correlate expression of proteins in ErbB family signaling pathways with the clinical efficacy of lapatinib
Tue Jan 05 00:00:00 UTC 2016
Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass.
Oncotarget
Yang CC,Fazli L,Loguercio S,Zharkikh I,Aza-Blanc P,Gleave ME,Wolf DA
MA5-14336 was used in Western Blotting to identify CSK downregulation as a principal driver of SRC activation and castration resistance.
Tue Sep 08 00:00:00 UTC 2015
CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point.
PLoS genetics
Bisteau X,Paternot S,Colleoni B,Ecker K,Coulonval K,De Groote P,Declercq W,Hengst L,Roger PP
MA5-14336 was used in western blot to study the roles CDK7 and p21 in regulating the T172 phosphorylation of CDK4 at the restriction point
Wed May 01 00:00:00 UTC 2013
Live-cell imaging visualizes frequent mitotic skipping during senescence-like growth arrest in mammary carcinoma cells exposed to ionizing radiation.
International journal of radiation oncology, biology, physics
Suzuki M,Yamauchi M,Oka Y,Suzuki K,Yamashita S
MA5-14336 was used in immunocytochemistry to visualize mitotic skipping during senescence-like growth arrest in mammary carcinoma cells exposed to ionizing radiation
Fri Jun 01 00:00:00 UTC 2012
Human embryonic stem cells suffer from centrosomal amplification.
Stem cells (Dayton, Ohio)
Holubcová Z,Matula P,Sedláčková M,Vinarský V,Doležalová D,Bárta T,Dvořák P,Hampl A
MA5-14336 was used in western blot to investigate the presence of supernumerary centrosomes in human embryonic stem cells
Sat Jan 01 00:00:00 UTC 2011
Neisseria gonorrhoeae infection induces altered amphiregulin processing and release.
PloS one
Löfmark S,de Klerk N,Aro H
MA5-14336 was used in western blot to report that infection with N. gonorrhoeae causes altered amphiregulin processing and release in human epithelial cells
Thu Jan 27 00:00:00 UTC 2011
Human embryonic stem cells are capable of executing G1/S checkpoint activation.
Stem cells (Dayton, Ohio)
Bárta T,Vinarský V,Holubcová Z,Dolezalová D,Verner J,Pospísilová S,Dvorák P,Hampl A
MA5-14336 was used in western blot to study the ability of human embryonic stem cells to execute G1/S checkpoint activation
Thu Jul 01 00:00:00 UTC 2010
Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cells.
BMC biology
Rico-Bautista E,Yang CC,Lu L,Roth GP,Wolf DA
MA5-14336 was used in western blot to test if small molecules can restore p27 expression in cancer cells
Thu Dec 23 00:00:00 UTC 2010
Potent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen.
BMC cancer
Cimica V,Smith ME,Zhang Z,Mathur D,Mani S,Kalpana GV
MA5-14336 was used in western blot to study the inhibitory effect of combined treatment with flavopiridol and 4OH-tamoxifen on rhabdoid tumor cell growth
Fri Nov 19 00:00:00 UTC 2010
E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
International journal of cancer
Chimploy K,Díaz GD,Li Q,Carter O,Dashwood WM,Mathews CK,Williams DE,Bailey GS,Dashwood RH
MA5-14336 was used in western blot to investigate the cellular effects of chlorophyllin treatment
Sun Nov 01 00:00:00 UTC 2009
Multitarget therapy of malignant cancers by the head-to-tail tandem array multiple shRNAs expression system.
Cancer gene therapy
Cheng TL,Teng CF,Tsai WH,Yeh CW,Wu MP,Hsu HC,Hung CF,Chang WT
MA5-14336 was used in western blot to evaluate an shRNA expression system for cancer therapy
Mon Jun 01 00:00:00 UTC 2009
Differences in the tumor microenvironment between African-American and European-American breast cancer patients.
PloS one
Martin DN,Boersma BJ,Yi M,Reimers M,Howe TM,Yfantis HG,Tsai YC,Williams EH,Lee DH,Stephens RM,Weissman AM,Ambs S
MA5-14336 was used in immunohistochemistry to compare tumor microenvironments between African-American and European-American breast cancer patients
Mon Apr 13 00:00:00 UTC 2009
Inhibition of prostate cancer growth by muscadine grape skin extract and resveratrol through distinct mechanisms.
Cancer research
Hudson TS,Hartle DK,Hursting SD,Nunez NP,Wang TT,Young HA,Arany P,Green JE
MA5-14336 was used in western blot to study the distinct mechanisms by which muscadine grape skin extract and resveratrol inhibit prostate cancer cell growth
Sat Sep 01 00:00:00 UTC 2007
Neisseria gonorrhoeae infection causes a G1 arrest in human epithelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jones A,Jonsson AB,Aro H
MA5-14336 was used in western blot to elucidate how Neisseria gonorrhoeae affects the cell cycle of human cells
Thu Feb 01 00:00:00 UTC 2007
Differential apoptosis by gallotannin in human colon cancer cells with distinct p53 status.
Molecular carcinogenesis
Al-Ayyoubi S,Gali-Muhtasib H
MA5-14336 was used in western blot to elucidate how treatment with gallotannin prevents cancer
Thu Mar 01 00:00:00 UTC 2007
Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.
The Journal of pharmacology and experimental therapeutics
Wiseman DA,Werner SR,Crowell PL
MA5-14336 was used in western blot to study the role of p21(Cip1) and p27(Kip1) in the induction of cell cycle arrest in human panceatic adenocarcinoma cells by isoprenoids
Thu Mar 01 00:00:00 UTC 2007
Association of breast cancer outcome with status of p53 and MDM2 SNP309.
Journal of the National Cancer Institute
Boersma BJ,Howe TM,Goodman JE,Yfantis HG,Lee DH,Chanock SJ,Ambs S
MA5-14336 was used in immunohistochemistry to study the association between p53 and MDM2 SNP309 and breast cancer survival
Wed Jul 05 00:00:00 UTC 2006
Optimization of endometrial preparation results in a normal endometrial function test (EFT) and good reproductive outcome in donor ovum recipients.
Journal of assisted reproduction and genetics
Kliman HJ,Honig S,Walls D,Luna M,McSweet JC,Copperman AB
MA5-14336 was used in immunohistochemistry to investigate the predictive value of endometrial function test in the characterization of uterine preparation of recipients using donor oocytes
Wed Jan 24 00:00:00 UTC 2007
Increase in Ara-C cytotoxicity in the presence of valproate, a histone deacetylase inhibitor, is associated with the concurrent expression of cyclin D1 and p27(Kip 1) in acute myeloblastic leukemia cells.
Leukemia research
Siitonen T,Koistinen P,Savolainen ER
MA5-14336 was used in western blot to investigate the effect of valproate on Ara-C cytotoxicity in acute myeloblastic leukemia cells and its mechanism
Tue Nov 01 00:00:00 UTC 2005
Tumor suppressor p16INK4a determines sensitivity of human cells to transformation by cooperating cellular oncogenes.
Cancer cell
Drayton S,Rowe J,Jones R,Vatcheva R,Cuthbert-Heavens D,Marshall J,Fried M,Peters G
MA5-14336 was used in western blot to study the role of tumor suppressor p16INK4a in the sensitivity of human cells to oncogenic transformation
Wed Oct 01 00:00:00 UTC 2003
Improved endometrial assessment using cyclin E and p27.
Fertility and sterility
Dubowy RL,Feinberg RF,Keefe DL,Doncel GF,Williams SC,McSweet JC,Kliman HJ
MA5-14336 was used in immunohistochemistry to evaluate cyclin E and p27 as developmental markers for endometrium
Tue Jul 01 00:00:00 UTC 2003
The cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase inhibitory activity of p57(KIP2) by interacting with its cyclin-binding domain.
The Journal of biological chemistry
Joaquin M,Watson RJ
MA5-14336 was used in western blot to study the interaction between cell cycle-regulated B-Myb transcription factor and p57KIP2
Fri Nov 07 00:00:00 UTC 2003
Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest.
European journal of cancer (Oxford, England : 1990)
Murillo G,Salti GI,Kosmeder JW,Pezzuto JM,Mehta RG
MA5-14336 was used in western blot to study the induction of apoptosis and cell cycle arrest in colon cancer cells by the antiproliferative agent deguelin
Sun Dec 01 00:00:00 UTC 2002
The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.
BMC cell biology
Lu L,Schulz H,Wolf DA
MA5-14336 was used in western blot to assess the role of the SKP2 F-box protein in p27 regulation in prostate cancer.
Tue Aug 20 00:00:00 UTC 2002
Dominant negative c-jun inhibits activation of the cyclin D1 and cyclin E kinase complexes.
Molecular biology of the cell
Hennigan RF,Stambrook PJ
Published figure using Cyclin E monoclonal antibody (Product # MA5-14336) in Western Blot
Wed Aug 01 00:00:00 UTC 2001
High-throughput tissue microarray analysis of cyclin E gene amplification and overexpression in urinary bladder cancer.
The American journal of pathology
Richter J,Wagner U,Kononen J,Fijan A,Bruderer J,Schmid U,Ackermann D,Maurer R,Alund G,Knönagel H,Rist M,Wilber K,Anabitarte M,Hering F,Hardmeier T,Schönenberger A,Flury R,Jäger P,Fehr JL,Schraml P,Moch H,Mihatsch MJ,Gasser T,Kallioniemi OP,Sauter G
MA5-14336 was used in immunohistochemistry to study the role of cyclin E amplification and overexpression in urinary bladder cancer using high throughput tissue microarrays
Fri Sep 01 00:00:00 UTC 2000
