NeoBiotechnologies

Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Recombinant Rabbit Monoclonal Antibody (KRT10/7804R)

Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Antibody (3858-RBM14-P1ABX) in IHC (P)

IHC analysis of Formalin-fixed, paraffin-embedded human skin. Stained using KRT10/7804R at 2 µg/mL in PBS for 30 min RT. HIER: Tris/EDTA, pH9.0, 45 min. 2 °: HRP-polymer, 30 min. DAB, 5 min.

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产品信息

3858-RBM14-P1ABX

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

2 µg/mL

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG, kappa

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

KRT10/7804R

抗原

Recombinant human fragment (around aa 484-584) of human KRT10 protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

靶标信息

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.

仅用于科研。不用于诊断过程。未经明确授权不得转售。