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产品信息
16572-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Cytokeratin 4 Fusion Protein Ag9854 (184-534 aa encoded by BC042174)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: NLLQQQTTT TSSKNLEPLF ETYLSVLRKQ LDTLGNDKGR LQSELKTMQD SVEDFKTKYE EEINKRTAAE NDFVVLKKDV DAAYLNKVEL EAKVDSLNDE INFLKVLYDA ELSQMQTHVS DTSVVLSMDN NRNLDLDSII AEVRAQYEEI AQRSKAEAEA LYQTKVQQLQ ISVDQHGDNL KNTKSEIAEL NRMIQRLRAE IENIKKQCQT LQVSVADAEQ RGENALKDAH SKRVELEAAL QQAKEELARM LREYQELMSV KLALDIEIAT YRKLLEGEEY RMSGECQSAV SISVVSGSTS TGGISGGLGS GSGFGLSSGF GSGSGSGFGF GGSVSGSSSS KIISTTTLNK RR (184-534 aa encoded by BC042174)
靶标信息
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9-7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CK-4; cytokeratin 4; Cytokeratin-4; K4; keratin 4, type II; Keratin, type II cytoskeletal 4; Keratin-4; Type-II keratin Kb4
基因别名: CK-4; CK4; CYK4; K4; KRT4; WSN1
UniProt ID: (Human) P19013
Entrez Gene ID: (Human) 3851
