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Immunogen sequence: GSTSTGGISG GLGSGSGFGL SSGFGSGSGS GFGFGGSVSG SSSSKIISTT TLNKRR
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9-7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CK-4; cytokeratin 4; Cytokeratin-4; K4; keratin 4, type II; Keratin, type II cytoskeletal 4; Keratin-4; Type-II keratin Kb4
基因别名: CK-4; CK4; CYK4; K4; KRT4; WSN1
UniProt ID: (Human) P19013
Entrez Gene ID: (Human) 3851