Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 24
Cytokeratin 8 Antibody (10384-1-AP) in ICC/IF
Immunofluorescent analysis of (-20°C Methanol) fixed HeLa cells using Cytokeratin 8 antibody (Product # 10384-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).
产品信息
10384-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Cytokeratin 8 Fusion Protein Ag0488 (1-483 aa encoded by BC000654)
偶联物
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSIRVTQKS YKVSTSGPRA FSSRSYTSGP GSRISSSSFS RVGSSNFRGG LGGGYGGASG MGGITAVTVN QSLLSPLVLE VDPNIQAVRT QEKEQIKTLN NKFASFIDKV RFLEQQNKML ETKWSLLQQQ KTARSNMDNM FESYINNLRR QLETLGQEKL KLEAELGNMQ GLVEDFKNKY EDEINKRTEM ENEFVLIKKD VDEAYMNKVE LESRLEGLTD EINFLRQLYE EEIRELQSQI SDTSVVLSMD NSRSLDMDSI IAEVKAQYED IANRSRAEAE SMYQIKYEEL QSLAGKHGDD LRRTKTEISE MNRNISRLQA EIEGLKGQRA SLEAAIADAE QRGELAIKDA NAKLSELEAA LQRAKQDMAR QLREYQELMN VKLALDIEIA TYRKLLEGEE SRLESGMQNM SIHTKTTSGY AGGLSSAYGG LTSPGLSYSL GSSFGSGAGS SSFSRTSSSR AVVVKKIETR DGKLVSESSD VLPK (1-483 aa encoded by BC000654)
靶标信息
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CK-8; cytokeratin 8; Cytokeratin endo A; Cytokeratin-8; K8; keratin 8, type II; keratin complex 2, basic, gene 8; Keratin, type II cytoskeletal 8; Keratin-8; Type-II keratin Kb8
基因别名: AA960620; AL022697; AU019895; CARD2; CK-8; CK8; CYK8; CYKER; EndoA; K2C8; K8; KO; Krt-2.8; Krt2-8; KRT8
UniProt ID: (Human) P05787, (Mouse) P11679, (Rat) Q10758
Entrez Gene ID: (Human) 3856, (Mouse) 16691, (Rat) 25626
cell morphogenesis involved in differentiation
multicellular organism development
tumor necrosis factor-mediated signaling pathway
sarcomere organization
response to hydrostatic pressure
response to other organism
cell differentiation involved in embryonic placenta development
extrinsic apoptotic signaling pathway
hepatocyte apoptotic process
viral process
