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MA1-06317 detects cytokeratin 8 in human samples.
MA1-06317 has sucessfully been used in Western blotting, FACS, immunocytochemistry and immunohistochemistry.
The MA1-06317 immunogen is a cytoskeleton preparation containing cytokeratin 8.
Store at 4ºC or at -20ºC in small aliquots.
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。