Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 3
DCAF7 Antibody (MA5-44858) in IHC (P)
Immunohistochemistry analysis of WDR68 in paraffin-embedded human prostate tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with WDR68 Monoclonal antibody (Product # MA5-44858) using a dilution of 1:200 for 30 minutes a... View More
产品信息
MA5-44858
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JE61-64
抗原
Synthetic peptide within human WDR68 aa 199-248/342.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 0.05% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2931314
靶标信息
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR68 (WD repeat-containing protein 68), also known as DCAF7 (DDB1- and CUL4- associated factor 7), HAN11 or WDR68, is a 342 amino acid protein that belongs to the WD repeat DCAF7 family and contains 4 WD repeats. Localizing to the cytoplasm and nucleus, WDR68 is involved in protein modification and ubiquitination pathways, and interacts directly with Dyrk1A, Dyrk1B and Dia 1. WDR68 is involved in craniofacial development, and may be involved in skin development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DDB1- and CUL4-associated factor 7; human anthocyanin; seven-WD-repeat protein of the AN11 family-1; WD repeat domain 68; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; WD-repeat protein
基因别名: 1700012F10Rik; 2610037L01Rik; AN11; C86529; DCAF7; HAN11; RGD1305140; SWAN-1; WDR68
UniProt ID: (Human) P61962, (Mouse) P61963
Entrez Gene ID: (Human) 10238, (Mouse) 71833, (Rat) 303602
