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产品信息
PA5-64960
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2662055
产品详细信息
Immunogen sequence: TSSVNGTPGSQ LSTPRSGKSP SPSPTSPGSL RKQRSSQHGG SSTSLASTKV CSSMDENDGP GEEVSEEGFQ IPATITERYK VGRTIGDGNF AVVKECVERS TAREYALKII K
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 96%.
靶标信息
DCAMKL1 (DCLK1) serine/threonine kinase or DCLK1 or doublecortin-like kinase 1 contains two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (which shows substantial homology to Ca2+/calmodulin-dependent protein kinase), and a serine/proline-rich domain in between the doublecortin and the protein kinase domains (which mediates multiple protein-protein interactions). DCAMKL1 is a microtubule-associated kinase that can undergo autophosphorylation. DCAMKL1 has microtubule-polymerizing activity that is independent of its protein kinase activity. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis.
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生物信息学
蛋白别名: Doublecortin domain-containing protein 3A; Doublecortin-like and CAM kinase-like 1; Doublecortin-like kinase 1; RP11-113P14.1; Serine/threonine-protein kinase DCLK1
基因别名: CL1; CLICK1; DCAMKL1; DCDC3A; DCLK; DCLK1; KIAA0369
UniProt ID: (Human) O15075
Entrez Gene ID: (Human) 9201
