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产品信息
PA5-23956
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 656-683 amino acids from the central region of human DDX11
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2541456
靶标信息
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX11 encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. DDX11 is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genomestability.
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生物信息学
蛋白别名: ATP-dependent DNA helicase DDX11; CHL1-like helicase homolog; CHL1-related helicase gene-1; CHL1-related protein 1; DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae); DEAD/H box protein 11; DEAD/H-box protein 11; DNA 5'-3' helicase DDX11; hCHLR1; Keratinocyte growth factor-regulated gene 2 protein; KRG-2; probable ATP-dependent RNA helicase DDX11
基因别名: 4732462I11Rik; CHL1; CHLR1; DDX11; essa15a; KRG2; WABS
UniProt ID: (Human) Q96FC9, (Mouse) Q6AXC6
Entrez Gene ID: (Human) 1663, (Mouse) 320209
double-stranded DNA binding
single-stranded DNA binding
RNA binding
ATP-dependent DNA helicase activity
helicase activity
protein binding
ATP binding
DNA-dependent ATPase activity
metal ion binding
4 iron, 4 sulfur cluster binding
nucleotide binding
nucleic acid binding
DNA binding
ATP-dependent helicase activity
hydrolase activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
iron-sulfur cluster binding
DNA helicase
