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Antibody detects endogenous levels of total DEFB132.
Beta-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, beta-defensins are developmentally regulated. The family of beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many beta-defensins also are involved in sperm maturation and capacitation. beta-defensin 32, also known as beta-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BD-32; Beta-defensin 132; Beta-defensin 32; Defensin HEL-75; Defensin, beta 132; defensin, beta 32; RP5-1103G7.6
基因别名: BD-32; DEFB-32; DEFB132; DEFB32; HEL-75; KFLL827; UNQ827; UNQ827/PRO1754
UniProt ID: (Human) Q7Z7B7
Entrez Gene ID: (Human) 400830
分子生物学功能:
antimicrobial response protein
defense/immunity protein