Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: PSPPESPQIL APTKPNFDIA WTSQPLDPSS DPSSLEDPRA RPPKALLAER AHLQPREEPG ALNSPATPTS NCQKSQPSSR PRVADLKKCF E
Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 45%.
Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Connecdenn 3; DENN domain-containing protein 1C; DENN/MADD domain containing 1C; family with sequence similarity 31, member C; Protein FAM31C
基因别名: DENND1C; FAM31C
UniProt ID: (Human) Q9H5Z2
Entrez Gene ID: (Human) 79958