Product References
Targeting diacylglycerol kinase α impairs lung tumorigenesis by inhibiting cyclin D3.
Thoracic cancer
Zhou D,Liu T,Rao X,Jie X,Chen Y,Wu Z,Deng H,Zhang D,Wang J,Wu G
Mon May 01 00:00:00 UTC 2023
Targeting diacylglycerol kinase α impairs lung tumorigenesis by inhibiting cyclin D3.
Thoracic cancer
Zhou D,Liu T,Rao X,Jie X,Chen Y,Wu Z,Deng H,Zhang D,Wang J,Wu G
Mon May 01 00:00:00 UTC 2023
Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction.
Frontiers in immunology
Velnati S,Centonze S,Rossino G,Purghè B,Antona A,Racca L,Mula S,Ruffo E,Malacarne V,Malerba M,Manfredi M,Graziani A,Baldanzi G
Fri May 19 00:00:00 UTC 2023
Wiskott-Aldrich syndrome protein interacts and inhibits diacylglycerol kinase alpha promoting IL-2 induction.
Frontiers in immunology
Velnati S,Centonze S,Rossino G,Purghè B,Antona A,Racca L,Mula S,Ruffo E,Malacarne V,Malerba M,Manfredi M,Graziani A,Baldanzi G
Fri May 19 00:00:00 UTC 2023
Combination therapy for hepatocellular carcinoma with diacylglycerol kinase alpha inhibition and anti-programmed cell death-1 ligand blockade.
Cancer immunology, immunotherapy : CII
Okada N,Sugiyama K,Shichi S,Shirai Y,Goto K,Sakane F,Kitamura H,Taketomi A
Fri Apr 01 00:00:00 UTC 2022
Selective inhibitors of bromodomain BD1 and BD2 of BET proteins modulate radiation-induced profibrotic fibroblast responses.
International journal of cancer
Liu CS,Rioja I,Bakr A,Veldwijk MR,Sperk E,Herskind C,Weichenhan D,Prinjha RK,Plass C,Schmezer P,Popanda O
Fri Jul 15 00:00:00 UTC 2022
Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness.
Frontiers in immunology
Manigat LC,Granade ME,Taori S,Miller CA,Vass LR,Zhong XP,Harris TE,Purow BW
Fri Jan 07 00:00:00 UTC 2022
Diacylglycerol kinase α inhibition cooperates with PD-1-targeted therapies to restore the T cell activation program.
Cancer immunology, immunotherapy : CII
Arranz-Nicolás J,Martin-Salgado M,Adán-Barrientos I,Liébana R,Del Carmen Moreno-Ortíz M,Leitner J,Steinberger P,Ávila-Flores A,Merida I
Mon Nov 01 00:00:00 UTC 2021
Diacylglycerol kinase ζ limits IL-2-dependent control of PD-1 expression in tumor-infiltrating T lymphocytes.
Journal for immunotherapy of cancer
Arranz-Nicolás J,Martin-Salgado M,Rodríguez-Rodríguez C,Liébana R,Moreno-Ortiz MC,Leitner J,Steinberger P,Ávila-Flores A,Merida I
Sun Nov 01 00:00:00 UTC 2020
DGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN-WEE1 Signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research
Li J,Pan C,Boese AC,Kang J,Umano AD,Magliocca KR,Yang W,Zhang Y,Lonial S,Jin L,Kang S
Wed Jul 15 00:00:00 UTC 2020
DGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN-WEE1 Signaling.
Clinical cancer research : an official journal of the American Association for Cancer Research
Li J,Pan C,Boese AC,Kang J,Umano AD,Magliocca KR,Yang W,Zhang Y,Lonial S,Jin L,Kang S
Wed Jul 15 00:00:00 UTC 2020
Diacylglycerol kinase ζ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapse.
Science signaling
Merino-Cortés SV,Gardeta SR,Roman-Garcia S,Martínez-Riaño A,Pineau J,Liebana R,Merida I,Dumenil AL,Pierobon P,Husson J,Alarcon B,Carrasco YR
Tue Apr 14 00:00:00 UTC 2020
Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering.
Nature chemical biology
Ware TB,Franks CE,Granade ME,Zhang M,Kim KB,Park KS,Gahlmann A,Harris TE,Hsu KL
Sat Feb 01 00:00:00 UTC 2020
Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels.
Nature communications
Novo D,Heath N,Mitchell L,Caligiuri G,MacFarlane A,Reijmer D,Charlton L,Knight J,Calka M,McGhee E,Dornier E,Sumpton D,Mason S,Echard A,Klinkert K,Secklehner J,Kruiswijk F,Vousden K,Macpherson IR,Blyth K,Bailey P,Yin H,Carlin LM,Morton J,Zanivan S,Norman JC
Thu Nov 29 00:00:00 UTC 2018
Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels.
Nature communications
Novo D,Heath N,Mitchell L,Caligiuri G,MacFarlane A,Reijmer D,Charlton L,Knight J,Calka M,McGhee E,Dornier E,Sumpton D,Mason S,Echard A,Klinkert K,Secklehner J,Kruiswijk F,Vousden K,Macpherson IR,Blyth K,Bailey P,Yin H,Carlin LM,Morton J,Zanivan S,Norman JC
Thu Nov 29 00:00:00 UTC 2018
Decreased LIPF expression is correlated with DGKA and predicts poor outcome of gastric cancer.
Oncology reports
Kong Y,Zheng Y,Jia Y,Li P,Wang Y
Sat Oct 01 00:00:00 UTC 2016
Decreased LIPF expression is correlated with DGKA and predicts poor outcome of gastric cancer.
Oncology reports
Kong Y,Zheng Y,Jia Y,Li P,Wang Y
Sat Oct 01 00:00:00 UTC 2016
Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis.
Nature communications
Weigel C,Veldwijk MR,Oakes CC,Seibold P,Slynko A,Liesenfeld DB,Rabionet M,Hanke SA,Wenz F,Sperk E,Benner A,Rösli C,Sandhoff R,Assenov Y,Plass C,Herskind C,Chang-Claude J,Schmezer P,Popanda O
Fri Mar 11 00:00:00 UTC 2016
Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis.
Nature communications
Weigel C,Veldwijk MR,Oakes CC,Seibold P,Slynko A,Liesenfeld DB,Rabionet M,Hanke SA,Wenz F,Sperk E,Benner A,Rösli C,Sandhoff R,Assenov Y,Plass C,Herskind C,Chang-Claude J,Schmezer P,Popanda O
Fri Mar 11 00:00:00 UTC 2016
Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.
Cancer discovery
Dominguez CL,Floyd DH,Xiao A,Mullins GR,Kefas BA,Xin W,Yacur MN,Abounader R,Lee JK,Wilson GM,Harris TE,Purow BW
Mon Jul 01 00:00:00 UTC 2013
Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.
Cancer discovery
Dominguez CL,Floyd DH,Xiao A,Mullins GR,Kefas BA,Xin W,Yacur MN,Abounader R,Lee JK,Wilson GM,Harris TE,Purow BW
Mon Jul 01 00:00:00 UTC 2013
A miR-297/hypoxia/DGK-α axis regulating glioblastoma survival.
Neuro-oncology
Kefas B,Floyd DH,Comeau L,Frisbee A,Dominguez C,Dipierro CG,Guessous F,Abounader R,Purow B
Sun Dec 01 00:00:00 UTC 2013
A miR-297/hypoxia/DGK-α axis regulating glioblastoma survival.
Neuro-oncology
Kefas B,Floyd DH,Comeau L,Frisbee A,Dominguez C,Dipierro CG,Guessous F,Abounader R,Purow B
Sun Dec 01 00:00:00 UTC 2013
Diacylglycerol kinase regulates tyrosinase expression and function in human melanocytes.
The Journal of investigative dermatology
Kawaguchi M,Valencia JC,Namiki T,Suzuki T,Hearing VJ
Sat Dec 01 00:00:00 UTC 2012
Diacylglycerol kinase regulates tyrosinase expression and function in human melanocytes.
The Journal of investigative dermatology
Kawaguchi M,Valencia JC,Namiki T,Suzuki T,Hearing VJ
Sat Dec 01 00:00:00 UTC 2012
Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.
Biochemical and biophysical research communications
Gellett AM,Kharel Y,Sunkara M,Morris AJ,Lynch KR
Fri Jun 15 00:00:00 UTC 2012
Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.
Biochemical and biophysical research communications
Gellett AM,Kharel Y,Sunkara M,Morris AJ,Lynch KR
Fri Jun 15 00:00:00 UTC 2012
