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DLD Antibody (PA5-70397) in IHC (P)
Immunohistochemical analysis of DLD in paraffin-embedded human pineal tissue. Sample was probed with a DLD polyclonal antibody (Product # PA5-70397) at a dilution of 1:100. Detection was performed with a donkey anti-Rabbit Cy3 secondary antibody at a dilution of 1:200. Images were taken at 20x magnification with an exposure time of 0.5-2.0 seconds.
产品信息
PA5-70397
产品规格
种属反应
Human,
Rat
已发表种属
Virus
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of human DLD
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2688322
产品详细信息
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Yeast: 86%; Zebrafish: 93%
靶标信息
This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: diaphorase; Dihydrolipoamide dehydrogenase; dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex); Dihydrolipoyl dehydrogenase, mitochondrial; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; Glycine cleavage system L protein; glycine cleavage system protein L; lipoamide dehydrogenase; lipoamide reductase; lipoyl dehydrogenase; OTTHUMP00000206744; OTTHUMP00000206746; OTTHUMP00000206748; OTTHUMP00000206749; PHE 3
基因别名: DLD; DLDD; DLDH; E3; GCSL; LAD; PHE3
UniProt ID: (Human) P09622, (Rat) Q6P6R2
Entrez Gene ID: (Human) 1738, (Rat) 298942
pyruvate metabolic process
tricarboxylic acid cycle
2-oxoglutarate metabolic process
mitochondrial electron transport, NADH to ubiquinone
proteolysis
lysine catabolic process
gastrulation
aging
branched-chain amino acid catabolic process
lipoate metabolic process
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of membrane potential
cell redox homeostasis
glyoxylate metabolic process
sperm capacitation
dihydrolipoamide metabolic process
mitochondrial acetyl-CoA biosynthetic process from pyruvate
acetyl-CoA biosynthetic process from pyruvate
detoxification of mercury ion
oxidation-reduction process
