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DLL1 Antibody (PA5-80554) in WB
Western Blot using DLL1 Polyclonal Antibody (Product # PA5-80554) at 1:500 dilution. Lane A: PC3 Membrane Lysate. Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 78 kDa. Observed band size: 62 kDa. (We are unsure of the identity of these extra bands).
产品信息
PA5-80554
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human DLL1 protein (Met1-Gly540)
偶联物
形式
Liquid
浓度
5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787855
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).^M
^M
This antibody has specificity for Human DLL1/Delta-1.
靶标信息
Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690
基因别名: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172
UniProt ID: (Human) O00548
Entrez Gene ID: (Human) 28514
cell fate determination
somitogenesis
somite specification
heart looping
marginal zone B cell differentiation
type B pancreatic cell development
Notch signaling pathway
Notch receptor processing
determination of left/right symmetry
compartment pattern specification
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
proximal/distal pattern formation
astrocyte development
regulation of somitogenesis
spinal cord development
cerebellar molecular layer formation
cerebellar Purkinje cell layer structural organization
hemopoiesis
cell differentiation
regulation of cell adhesion
negative regulation of epithelial cell differentiation
negative regulation of interleukin-10 production
negative regulation of glial cell apoptotic process
organ growth
regulation of growth
negative regulation of cell differentiation
negative regulation of epidermal cell differentiation
negative regulation of auditory receptor cell differentiation
negative regulation of myeloid cell differentiation
negative regulation of myoblast differentiation
negative regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of endocytosis
positive regulation of transcription from RNA polymerase II promoter
lateral inhibition
skeletal muscle tissue growth
regulation of skeletal muscle tissue growth
positive regulation of skeletal muscle tissue growth
neuron fate specification
inner ear development
regulation of neurogenesis
regulation of cell division
retina development in camera-type eye
retina morphogenesis in camera-type eye
Notch signaling pathway involved in arterial endothelial cell fate commitment
left/right axis specification
nephron development
proximal tubule development
loop of Henle development
clathrin-mediated endocytosis
endothelial tip cell fate specification
neuronal stem cell population maintenance
skin epidermis development
regulation of vascular endothelial growth factor signaling pathway
positive regulation of sprouting angiogenesis
regulation of energy homeostasis
