Abnova

DLL1 Monoclonal Antibody (4F8)

查看其他23个DLL1抗体

产品信息

H00028514-M01

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

-

免疫细胞化学 (ICC/IF)

10-100 µg/mL

-

酶联免疫吸附实验 (ELISA)

10 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

4F8

抗原

DLL1 (NP_005609, 18 a.a. approximately 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

产品详细信息

Immunogen sequence: QVWSSGVFEL KLQEFVNKKG LLGNRNCCRG GAGPPPCACR TFFRVCLKHY QASVSPEPPC TYGSAVTPVL GVDSFSLPDG GGADSAFSNP IR

靶标信息

Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690

查看更多收起

基因别名: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172

查看更多收起

UniProt ID: (Human) O00548

查看更多收起

Entrez Gene ID: (Human) 28514

查看更多收起

Notch binding calcium ion binding protein binding Tat protein binding scaffold protein binding

参与通路

cell fate determination somitogenesis somite specification heart looping marginal zone B cell differentiation type B pancreatic cell development Notch signaling pathway Notch receptor processing determination of left/right symmetry compartment pattern specification regulation of blood pressure positive regulation of cell proliferation negative regulation of cell proliferation proximal/distal pattern formation astrocyte development regulation of somitogenesis spinal cord development cerebellar molecular layer formation cerebellar Purkinje cell layer structural organization hemopoiesis cell differentiation regulation of cell adhesion negative regulation of epithelial cell differentiation negative regulation of interleukin-10 production negative regulation of glial cell apoptotic process organ growth regulation of growth negative regulation of cell differentiation negative regulation of epidermal cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of myeloid cell differentiation negative regulation of myoblast differentiation negative regulation of neuron differentiation positive regulation of Notch signaling pathway positive regulation of endocytosis positive regulation of transcription from RNA polymerase II promoter lateral inhibition skeletal muscle tissue growth regulation of skeletal muscle tissue growth positive regulation of skeletal muscle tissue growth neuron fate specification inner ear development regulation of neurogenesis regulation of cell division retina development in camera-type eye retina morphogenesis in camera-type eye Notch signaling pathway involved in arterial endothelial cell fate commitment left/right axis specification nephron development proximal tubule development loop of Henle development clathrin-mediated endocytosis endothelial tip cell fate specification neuronal stem cell population maintenance skin epidermis development regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis regulation of energy homeostasis