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DLL3 Antibody (MA5-43156) in Flow
Flow Cytometry analysis of DLL3 in untransfected HEK293 cells (green line) and transfected Human DLL3 HEK293 stable cells (red line) using DLL3 Monoclonal Antibody (Product # MA5-43156) (2 µL/1x10^6cells), washed and then followed by FITC-conjugated anti-Human IgG1 Fc antibody.
产品信息
MA5-43156
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
7B7
抗原
Recombinant Human DLL3 protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2912292
产品详细信息
Antibody tested in Indirect ELISA
靶标信息
Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: delta-like 3; Delta-like protein 3; Delta3; Drosophila Delta homolog 3
基因别名: DLL3; SCDO1
UniProt ID: (Human) Q9NYJ7
Entrez Gene ID: (Human) 10683
