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Sequence of this protein is as follows: YLALPERAEL AASLGLTQTQ VKIWFQNKRS KFKKLMKQGG AALEGSALAN GRALSAGSPP VPPGWNPNSS SGKGSGGNAG SYIPSYTSWY PSAHQEAMQQ PQLM
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-beta superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: distal-less homeo box 1; Homeobox protein DLX-1
基因别名: DLX1
UniProt ID: (Human) P56177
Entrez Gene ID: (Human) 1745
分子生物学功能:
homeodomain transcription factor