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Application
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DLX4 Antibody (PA1-16602) in IHC (F)
Immunohistochemical analysis of DLX4 in breast cancer cells and normal breast tissue. Frozen samples were incubated in DLX4 polyclonal antibody (Product # PA1-16602). Top Panel: BP1 antibody detected in breast cancer cells. Bottom Panel: Staining of normal breast tissue.
产品信息
PA1-16602
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide made specifically to the human BP1 protein sequence (residues 1-60). There is no homology to DLX4 or DLX7.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.1% sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2090709
产品详细信息
The target sequence has 82% sequence homology with mouse.
靶标信息
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta protein 1; distal-less homeo box 7; distal-less homeo box 9; Homeobox protein DLX-4; Homeobox protein DLX-7; Homeobox protein DLX-8
基因别名: BP1; DLX4; DLX7; DLX8; DLX9; OFC15
UniProt ID: (Human) Q92988
Entrez Gene ID: (Human) 1748
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
homeodomain transcription factor
