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The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. There are three alternatively spliced transcript variants encoding the same protein described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA ligase 1; DNA ligase I; ligase 1; ligase I, DNA, ATP-dependent; MGC117397; MGC130025; Polydeoxyribonucleotide synthase [ATP] 1
基因别名: LIG1
UniProt ID: (Human) P18858
Entrez Gene ID: (Human) 3978
分子生物学功能:
DNA ligase