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Invitrogen
DOPA Decarboxylase Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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DOPA Decarboxylase Antibody (PA5-47512) in ICC/IF
Immunocytochemistry analysis of DOPA Decarboxylase in immersion fixed IMR‚32 human neuroblastoma cell line. Samples were incubated in DOPA Decarboxylase polyclonal antibody (Product # PA5-47512) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to ... View More
产品信息
PA5-47512
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Sf 21-derived recombinant human Dopa Decarboxylase/DDC Met1-Glu480
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609231
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AADC; aromatic L-amino acid decarboxylase; Aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); HGNC:2719; L-Dopa decarboxylase
基因别名: AADC; DDC
UniProt ID: (Human) P20711, (Mouse) O88533, (Rat) P14173
Entrez Gene ID: (Human) 1644, (Mouse) 13195, (Rat) 24311
cellular amino acid metabolic process
circadian rhythm
multicellular organism aging
aminergic neurotransmitter loading into synaptic vesicle
isoquinoline alkaloid metabolic process
cellular response to drug
dopamine biosynthetic process
catecholamine biosynthetic process
serotonin biosynthetic process
indolalkylamine biosynthetic process
response to pyrethroid
phytoalexin metabolic process
cellular response to alkaloid
cellular response to growth factor stimulus
response to toxic substance
carboxylic acid metabolic process
dopamine metabolic process
