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产品信息
PA5-62490
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
Lot-Specific
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640768
产品详细信息
Immunogen sequence: SLEVSRSPRR SRRELEVRSP RQNKYSVLLP TYNERENLPL IVWLLVKSFS ESGINYEIII IDDGSPDGTR DVAEQLEKIY GSD^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 81%.
靶标信息
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dolichol monophosphate mannose synthase; Dolichol-phosphate mannose synthase subunit 1; Dolichol-phosphate mannosyltransferase subunit 1; Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; dolichyl-phosphate mannosyltransferase polypeptide 1 catalytic subunit; DPM synthase complex, catalytic subunit; DPM synthase subunit 1; Mannose-P-dolichol synthase subunit 1; MPD synthase subunit 1; OTTMUSP00000017164; RP23-391M18.1
基因别名: CDGIE; DPM1; MPDS
UniProt ID: (Human) O60762
Entrez Gene ID: (Human) 8813
