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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human DPP10.
A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first axons; four of which localize within the LD block strongly associated with asthma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: dipeptidyl peptidase 10; Dipeptidyl peptidase IV-related protein 3; Dipeptidyl peptidase X; Dipeptidyl peptidase-like protein 2; dipeptidyl-peptidase 10 (inactive); dipeptidyl-peptidase 10 (non-functional); DPL2; DPP X; DPRP-3; HGNC:20823; Inactive dipeptidyl peptidase 10; OTTHUMP00000203618
基因别名: DPL2; DPP10; DPPY; DPRP-3; DPRP3; KIAA1492
UniProt ID: (Human) Q8N608
Entrez Gene ID: (Human) 57628