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Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Horse, Rabbit, Xenopus (100%).
DPP6 encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A-type potassium channel modulatory protein DPP6; dipeptidyl aminopeptidase IV-related protein; Dipeptidyl aminopeptidase-like protein 6; Dipeptidyl aminopeptidase-related protein; Dipeptidyl peptidase 6; Dipeptidyl peptidase IV-like protein; dipeptidyl peptidase IV-related protein; Dipeptidyl peptidase VI; dipeptidyl-peptidase 6; dipeptidylpeptidase 6; dipeptidylpeptidase VI; DPP VI; DPPX; In(5)6H p; inversion, Chr 5, Harwell 6, proximal
基因别名: B930011P16Rik; D5Buc3; D5Buc4; D5Buc5; DPL1; DPP VI; Dpp-6; DPP6; DPPX; Gm1377; In(5)6H-p; MRD33; Peplb; Rw; VF2
UniProt ID: (Bovine) P42659, (Human) P42658, (Mouse) Q9Z218, (Rat) P46101
Entrez Gene ID: (Bovine) 281123, (Rabbit) 100344997, (Horse) 100063666, (Human) 1804, (Mouse) 13483, (Rat) 29272