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Positive Samples: SH-SY5Y, Rat brain
Immunogen sequence: GKIVFEDGNI NVNKGMGRFI PRKAFPEHLY QRVKIRNKVF GLQGVSRGMY DGPVYEVPAT PKYATPAPSA KSSPSKHQPP PIRNLHQSNF SLSGAQIDDN N
A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-terminal region; Dnm1p/Vps1p-like protein; DVLP; Dymple; dynamin 1-like; Dynamin family member proline-rich carboxyl-terminal domain less; Dynamin-1-like protein; Dynamin-like protein; dynamin-like protein 1; Dynamin-like protein 4; Dynamin-like protein IV; Dynamin-related protein 1; DYNIV 11; DYNIV-11; EC 3.6.5.5; FLJ41912; HdynIV; N-terminal region; VPS1
基因别名: DLP1; DNM1L; Dnml1; DRP1; DVLP; DYMPLE; EMPF; HDYNIV
UniProt ID: (Human) O00429, (Rat) O35303
Entrez Gene ID: (Human) 10059, (Rat) 114114