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Proteintech

DSG2 Polyclonal Antibody

7 篇参考文献

查看其他25个Desmoglein 2 (DSG2)抗体

抗体检测数据 (11)

Application

DSG2 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 11

DSG2 Antibody (21880-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed A431 cells using 21880-1-AP (DSG2 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

DSG2 Antibody in Immunocytochemistry (ICC/IF)

DSG2 Antibody in Immunocytochemistry (ICC/IF)

DSG2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

DSG2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

DSG2 Antibody in Western Blot (WB)

DSG2 Antibody in Western Blot (WB)

DSG2 Antibody in Western Blot (WB)

DSG2 Antibody in Western Blot (WB)

DSG2 Antibody in Western Blot (WB)

DSG2 Antibody in Western Blot (WB)

DSG2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

DSG2 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of (-20°C Ethanol) fixed A431 cells using 21880-1-AP (DSG2 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

DSG2 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of A431 cells using 21880-1-AP (DSG2 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

DSG2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue slide using (Product # 21880-1-AP) DSG2 antibody at dilution of 1:1,000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

DSG2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue slide using (Product # 21880-1-AP) DSG2 antibody at dilution of 1:1,000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

DSG2 Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 21880-1-AP (DSG2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

DSG2 Antibody in Western Blot (WB) — HepG2 cells were subjected to SDS PAGE followed by western blot with 21880-1-AP (DSG2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

DSG2 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 21880-1-AP (DSG2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

DSG2 Antibody in Western Blot (WB) — A549 cells were subjected to SDS PAGE followed by western blot with 21880-1-AP (DSG2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

DSG2 Antibody in Western Blot (WB) — A431 cells were subjected to SDS PAGE followed by western blot with 21880-1-AP (DSG2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

DSG2 Antibody in Western Blot (WB) — WB result of DSG2 antibody (Product # 21880-1-AP) 1:4,000, incubated at room temperature for 1.5 hours with sh-Control and sh-DSG2 transfected HEK-293 cells.

DSG2 Antibody in Immunoprecipitation (IP) — IP result of anti-DSG2 (IP:21880-1-AP, 4ug; Detection:21880-1-AP 1:1000) with HepG2 cells lysate 3600ug.

产品信息

21880-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:4,000

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:1,000

-

免疫细胞化学 (ICC/IF)

1:10-1:100

查看4篇已发表文章 4篇已发表文章

免疫沉淀 (IP)

0.5-4.0 µg

-

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

DSG2 Fusion Protein Ag16393 (819-1118 aa encoded by BC099655)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.23 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: GELDDRFLD DLGLKFKTLA EVCLGQKIDI NKEIEQRQKP ATETSMNTAS HSLCEQTMVN SENTYSSGSS FPVPKSLQEA NAEKVTQEIV TERSVSSRQA QKVATPLPDP MASRNVIATE TSYVTGSTMP PTTVILGPSQ PQSLIVTERV YAPASTLVDQ PYANEGTVVV TERVIQPHGG GSNPLEGTQH LQDVPYVMVR ERESFLAPSS GVQPTLAMPN IAVGQNVTVT ERVLAPASTL QSSYQIPTEN SMTARNTTVS GAGVPGPLPD FGLEESGHSN STITTSSTRV TKHSTVQHSY S (819-1118 aa encoded by BC099655)

靶标信息

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Plakophilin-3 Binds the Membrane and Filamentous Actin without Bundling F-Actin.

International journal of molecular sciences

Gupta J,Rangarajan ES,Troyanovsky RB,Indra I,Troyanovsky SM,Izard T

Mon May 29 00:00:00 UTC 2023

Inhibition of retinoid X receptor improved the morphology, localization of desmosomal proteins and paracellular permeability in three-dimensional cultures of mouse keratinocytes.

Microscopy (Oxford, England)

Ishikawa S,Nikaido M,Otani T,Ogata K,Iida H,Inai Y,Tamaoki S,Inai T

Mon Jun 06 00:00:00 UTC 2022

Plakophilin 3 and Par3 facilitate desmosomes' association with the apical junctional complex.

Molecular biology of the cell

Indra I,Troyanovsky RB,Green KJ,Troyanovsky SM

Wed Sep 01 00:00:00 UTC 2021

Desmoglein 2 (DSG2) Is A Receptor of Human Adenovirus Type 55 Causing Adult Severe Community-Acquired Pneumonia.

Virologica Sinica

Zhang J,Ma K,Wang X,Jiang Y,Zhao S,Ou J,Lan W,Guan W,Wu X,Zheng H,Yang B,Wan C,Zhao W,Wu J,Zhang Q

Wed Dec 01 00:00:00 UTC 2021

O-glycan initiation directs distinct biological pathways and controls epithelial differentiation.

EMBO reports

Bagdonaite I,Pallesen EM,Ye Z,Vakhrushev SY,Marinova IN,Nielsen MI,Kramer SH,Pedersen SF,Joshi HJ,Bennett EP,Dabelsteen S,Wandall HH

Thu Jun 04 00:00:00 UTC 2020

Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Zhang J,Li Z,Qie M,Zheng R,Shetty J,Wang J

Mon Aug 01 00:00:00 UTC 2016

Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Zhang J,Li Z,Qie M,Zheng R,Shetty J,Wang J

Mon Aug 01 00:00:00 UTC 2016

Helicobacter pylori dwelling on the apical surface of gastrointestinal epithelium damages the mucosal barrier through direct contact.

Helicobacter

Zhang C,Zhang H,Yu L,Cao Y

Wed Oct 01 00:00:00 UTC 2014

Helicobacter pylori dwelling on the apical surface of gastrointestinal epithelium damages the mucosal barrier through direct contact.

Helicobacter

Zhang C,Zhang H,Yu L,Cao Y

Wed Oct 01 00:00:00 UTC 2014

生物信息学

蛋白别名: ARVC10; ARVD10; Cadherin family member 5; CMD1BB; desmoglein 2; Desmoglein-2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037

基因别名: AA408168; CDHF5; D18Ertd293e; DSG2; HDGC

UniProt ID: (Human) Q14126, (Mouse) O55111

Entrez Gene ID: (Human) 1829, (Mouse) 13511, (Rat) 307562

calcium ion binding cell adhesion molecule binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication metal ion binding cadherin

参与通路

desmosome organization Purkinje myocyte development cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules response to progesterone maternal process involved in female pregnancy bundle of His cell-Purkinje myocyte adhesion involved in cell communication regulation of heart rate by cardiac conduction regulation of ventricular cardiac muscle cell action potential ventricular cardiac muscle cell action potential bundle of His cell to Purkinje myocyte communication