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产品信息
MA5-25361
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI1B2
抗原
Full length human recombinant protein of DTNA produced in HEK293T cell
偶联物
Unconjugated
形式
Liquid
浓度
0.72 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723096
靶标信息
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-dystrobrevin; DTN-A; Dystrobrevin alpha; dystrobrevin, alpha; Dystrophin-related protein 3
基因别名: D18S892E; DRP3; DTN; DTN-A; DTNA; LVNC1
UniProt ID: (Human) Q9Y4J8
Entrez Gene ID: (Human) 1837
