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产品信息
67209-1-IG
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
2D4F8
抗原
DTX2 Fusion Protein Ag12022
偶联物
形式
Liquid
浓度
1000 µg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Aliquoting is unnecessary for -20°C storage.
靶标信息
DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: deltex 2, E3 ubiquitin ligase; deltex homolog 2; Deltex2; hDTX2; Probable E3 ubiquitin-protein ligase DTX2; Protein deltex-2; RING finger protein 58; RING-type E3 ubiquitin transferase DTX2; zinc ion binding protein
基因别名: DTX2; KIAA1528; RNF58
UniProt ID: (Human) Q86UW9
Entrez Gene ID: (Human) 113878
