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产品信息
25304-1-AP
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DTX3 Fusion Protein Ag18111 (1-249 aa encoded by BC114498)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSFVLSRMA ACGGTCKNKV TVSKPVWDFL SKETPARLAR LREEHRVSIL IDGETSDIYV LQLSPQGPPP APPNGLYLAR KALKGLLKEA EKELKKAQRQ GELMGCLALG GGGEHPEMHR AGPPPLRAAP LLPPGARGLP PPPPPLPPPL PPRLREEAEE QESTCPICLG EIQNAKTLEK CRHSFCEGCI TRALQVKKAC PMCGRFYGQL VGNQPQNGRM LVSKDATLLL PSYEKYGTIV IQYVFPPGVQ (1-249 aa encoded by BC114498)
靶标信息
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: deltex 3, E3 ubiquitin ligase; deltex homolog 3; Deltex3; FLJ34766; mDTX3; MGC138863; MGC138864; Probable E3 ubiquitin-protein ligase DTX3; Protein deltex-3; RING finger protein 154; RING-type E3 ubiquitin transferase DTX3
基因别名: Deltex3; DTX3; mg310; RNF154
UniProt ID: (Human) Q8N9I9, (Mouse) Q80V91
Entrez Gene ID: (Human) 196403, (Mouse) 80904
protein binding
zinc ion binding
ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
