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Proteintech

DVL1 Polyclonal Antibody

8 篇参考文献

查看其他8个DVL1抗体

说明书

实验方案

技术支持

货号 27384-1-AP

此产品在中国无法购买

150 µL

说明书

实验方案

技术支持

抗体检测数据 (6)

Application

DVL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 6

DVL1 Antibody (27384-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using 27384-1-AP (DVL1 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

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产品信息

27384-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

查看6篇已发表文章 6篇已发表文章

免疫组化 (IHC)

查看2篇已发表文章 2篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:500

产品规格

种属反应

Human, Mouse

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

DVL1 Fusion Protein Ag26055 (283-416 aa encoded by BC050454)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.23 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: LGQGYPYQY PGPPPCFPPA YQDPGFSYGS GSTGSQQSEG SKSSGSTRSS RRAPGREKER RAAGAGGSGS ESDHTAPSGV GSSWRERPAG QLSRGSSPRS QASATAPGLP PPHPTTKAYT VVGGPPGGPP VRELA (283-416 aa encoded by BC050454)

靶标信息

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cellproliferation, acting as a transducer molecule for developmentalprocesses, including segmentation and neuroblast specification.DVL1 is a candidate gene for neuroblastomatous transformation. TheSchwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2Ahave been mapped to the same region as DVL1. The phenotypes ofthese diseases may be consistent with defects which might beexpected from aberrant expression of a DVL gene during development.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components.

Biological trace element research

Lin T,Tao J,Chen Y,Zhang Y,Li F,Zhang Y,Han X,Zhao Z,Liu G,Li H

Tue Mar 01 00:00:00 UTC 2022

ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer.

Journal of experimental & clinical cancer research : CR

Dong S,Liang S,Cheng Z,Zhang X,Luo L,Li L,Zhang W,Li S,Xu Q,Zhong M,Zhu J,Zhang G,Hu S

Sat Jan 08 00:00:00 UTC 2022

Excess folic acid supplementation before and during pregnancy and lactation activates β-catenin in the brain of male mouse offspring.

Brain research bulletin

Wu Q,Zhou D,Wu R,Shi R,Shen X,Jin N,Gu J,Gu JH,Liu F,Chu D

Sat Jan 01 00:00:00 UTC 2022

The m⁶ A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Yu J,She Y,Yang L,Zhuang M,Han P,Liu J,Lin X,Wang N,Chen M,Jiang C,Zhang Y,Yuan Y,Ji SJ

Mon Nov 01 00:00:00 UTC 2021

Lycopene-Loaded Microemulsion Regulates Neurogenesis in Rats with Aβ-Induced Alzheimer's Disease Rats Based on the Wnt/β-catenin Pathway.

Neural plasticity

Ning WJ,Lv RJ,Xu N,Hou XY,Shen C,Guo YL,Fan ZY,Cao N,Liu XP

Fri Feb 04 00:00:00 UTC 2022

cDNA expression library screening revealed novel functional genes involved in clear cell carcinogenesis of the ovary in vitro.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

Yamada Y,Miyamoto T,Higuchi S,Ono M,Kobara H,Asaka R,Ando H,Suzuki A,Shiozawa T

Fri Jan 01 00:00:00 UTC 2021

Dishevelled-1 regulated apoptosis through NF-κB in cerebral ischemia/reperfusion injury in rats.

Neuroscience letters

Zhang X,Zhang X,Li X,Ma J,Xie D,Jiang N

Mon Mar 23 00:00:00 UTC 2020

Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma.

Theranostics

Song J,Xie C,Jiang L,Wu G,Zhu J,Zhang S,Tang M,Song L,Li J

Mon Aug 19 00:00:00 UTC 2019

Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma.

Theranostics

Song J,Xie C,Jiang L,Wu G,Zhu J,Zhang S,Tang M,Song L,Li J

Mon Aug 19 00:00:00 UTC 2019

生物信息学

蛋白别名: dishevelled 1 (homologous to Drosophila dsh); dishevelled, dsh homolog 1; Dishevelled-1; Dishevelled-1-like; DSH homolog 1; DSH homolog 1-like; MGC54245; RP5-890O3.5; Segment polarity protein dishevelled homolog DVL-1

基因别名: DRS2; DVL; DVL1; DVL1L1; DVL1P1; mKIAA4029

UniProt ID: (Human) O14640, (Mouse) P51141

Entrez Gene ID: (Human) 1855, (Mouse) 13542

功能

molecular_function frizzled binding protein binding beta-catenin binding enzyme binding protein kinase binding identical protein binding Rac GTPase binding scaffold/adaptor protein

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