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产品信息
12240-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DYRK1B Fusion Protein Ag2883 (38-343 aa encoded by BC018751)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RDATSAPLR KLSVDLIKTY KHINEVYYAK KKRRAQQAPP QDSSNKKEKK VLNHGYDDDN HDYIVRSGER WLERYEIDSL IGKGSFGQVV KAYDHQTQEL VAIKIIKNKK AFLNQAQIEL RLLELMNQHD TEMKYYIVHL KRHFMFRNHL CLVFELLSYN LYDLLRNTHF RGVSLNLTRK LAQQLCTALL FLATPELSII HCDLKPENIL LCNPKRSAIK IVDFGSSCQL GQRIYQYIQS RFYRSPEVLL GTPYDLAIDM WSLGCILVEM HTGEPLFSGS NEVDQMNRIV EVLGIPPAAM LDQAPKA (38-343 aa encoded by BC018751)
靶标信息
DYRK1B is a member of the DYRK family of protein kinases and is proposed to be involved in nuclear functions. Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. DYRK1B encodes the integrin beta 4 subunit, a receptor for the laminins. Mutations in DYRK1B are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for DYRK1B.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; DYRKB; Minibrain-related kinase; Mirk protein kinase
基因别名: AOMS3; DYRK1B; MIRK
UniProt ID: (Human) Q9Y463, (Mouse) Q9Z188
Entrez Gene ID: (Human) 9149, (Mouse) 13549, (Rat) 308468
transcription coactivator activity
protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
