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DYRK1B Antibody (PA5-14467) in IHC (P)
Immunohistochemistry analysis of DYRK1B in formalin-fixed and paraffin-embedded human cancer tissue. Samples were incubated with DYRK1B polyclonal antibody (Product # PA5-14467) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = he... View More
产品信息
PA5-14467
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 561-589 amino acids from the C-terminal region of human DYRK1B
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Ammonium sulfate precipitation, Size-exclusion - Dialysis
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2093805
靶标信息
DYRK1B is a member of the DYRK family of protein kinases and is proposed to be involved in nuclear functions. Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. DYRK1B encodes the integrin beta 4 subunit, a receptor for the laminins. Mutations in DYRK1B are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for DYRK1B.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; DYRKB; Minibrain-related kinase; Mirk protein kinase
基因别名: AOMS3; DYRK1B; MIRK
UniProt ID: (Human) Q9Y463, (Mouse) Q9Z188
Entrez Gene ID: (Human) 9149, (Mouse) 13549
transcription coactivator activity
protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
